PHARMACOLOGICAL EVALUATION OF ANTIOXIDANT, ANTIMICROBIAL AND PHYTOTOXIC ACTIVITIES OF CRUDE EXTRACT AND PURIFIED COMPOUND OF LONICERA QUINQUELOCULARIS HARDW

In this study crude extract and the pure compound of Lonicera quinquelocularis Hardw. plant was studied for antioxidant, antimicrobial and phytotoxic activities. The isolated pure compound showed highest antioxidant activities than the crude extract while the crude extract showed more potential of inhibiting growth of the fungal and bacterial strains as compared to its isolated compound. The DPPH and ABTS scavenging activities of the crude extract and isolated compound was increased with increasing concentrations. Crude extract inhibits the growth of Aspergillus fumigatus and Fusarium solani 65 and 70%, respectively while the isolated compound showed 22 and 44% inhibition of A. fumigatus and F. solani, respectively. Both the extract and purified compound also showed growth inhibition of bacterial strain Salmonella typhimurium. Moreover, the crude extract and the isolated compound significantly retard growth of maize seedlings.