Risk Factors for the Progression of Mild Cognitive Impairment to Dementia

被引：164
|
作者：
Campbell, Noll L. [1 ,2 ,3 ,4 ]
Unverzagt, Fred [5 ]
LaMantia, Michael A. [2 ,3 ,6 ]
Khan, Babar A. [2 ,3 ,6 ]
Boustani, Malaz A. [2 ,3 ,6 ]
机构：
[1] Purdue Univ, Coll Pharm, W Lafayette, IN 47907 USA
[2] Indiana Univ, Ctr Aging Res, Indianapolis, IN 46202 USA
[3] Regenstrief Inst Hlth Care, Indianapolis, IN 46202 USA
[4] Wishard Eskenazi Hlth Serv, Dept Pharm, Indianapolis, IN 46202 USA
[5] Indiana Univ Sch Med, Dept Psychiat, Indianapolis, IN 46202 USA
[6] Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA
来源：
CLINICS IN GERIATRIC MEDICINE | 2013年 / 29卷 / 04期
基金：
美国医疗保健研究与质量局;
关键词：
Mild cognitive impairment; Dementia; Risk factors; Genetics; Biomarkers; WHITE-MATTER HYPERINTENSITIES; CEREBROSPINAL-FLUID BIOMARKERS; PLASMA AMYLOID-BETA; ALZHEIMERS-DISEASE; METABOLIC SYNDROME; CSF BIOMARKERS; FOLLOW-UP; PREDICTS PROGRESSION; NATIONAL INSTITUTE; VASCULAR DEMENTIA;
D O I：
10.1016/j.cger.2013.07.009
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
The increasing prevalence of cognitive impairment among the older adult population warrants attention to the identification of practices that may minimize the progression of early forms of cognitive impairment, including the transitional stage of mild cognitive impairment (MCI), to permanent stages of dementia. This article identifies both markers of disease progress and risk factors linked to the progression of MCI to dementia. Potentially modifiable risk factors may offer researchers a point of intervention to modify the effect of the risk factor and to minimize the future burden of dementia.
引用
收藏
页码：873 / +
页数：22
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