Design and evaluation of a semantic approach for the homogeneous identification of events in eight patient databases: a contribution to the European EU-ADR project

被引：13

作者：

Avillach, Paul ^{[1
,2
]}

Joubert, Michel ^{[2
]}

Thiessard, Frantz ^{[1
]}

Trifiro, Gianluca ^{[3
]}

Dufour, Jean-Charles ^{[2
]}

Pariente, Antoine ^{[4
]}

Mougin, Fleur ^{[1
]}

Polimeni, Giovanni ^{[3
]}

Catania, Maria Antonietta ^{[3
]}

Giaquinto, Carlo ^{[5
]}

Mazzaglia, Giampiero ^{[6
]}

Fornari, Carla ^{[7
]}

Herings, Ron ^{[8
]}

Gini, Rosa ^{[9
]}

Hippisley-Cox, Julia ^{[10
]}

Molokhia, Mariam ^{[11
]}

Pedersen, Lars ^{[12
]}

Fourrier-Reglat, Annie ^{[4
]}

Sturkenboom, Miriam ^{[13
]}

Fieschi, Marius ^{[2
]}

机构：

[1] Uni Bordeaux 2, ISPED, LESIM, Bordeaux, France

[2] Uni Mediterranee, Fac Med, LERTIM, Marseille, France

[3] IRCCS Ctr Neurolesi Bonino Pulejo, Messina, Italy

[4] Uni Victor Segalen Bordeaux 2, INSERM, U 657, Bordeaux, France

[5] Pedianet Soc Serv Telemat SRL, Bordeaux, France

[6] Hlth Search Italian Coll Gen Practitioners, Bordeaux, France

[7] Univ Milano Bicocca, Ctr Publ Hlth, Milan, Italy

[8] PHARMO Cooperat UA, Amsterdam, Netherlands

[9] Reg Hlth Agcy Tuscany, Florence, Italy

[10] Uni Nottingham, Nottingham, England

[11] London Sch Hyg & Trop Med, London, England

[12] Aarhus Uni Hosp, Arhus Sygehus, Denmark

[13] Erasmus Uni, Med Ctr, IPCI Dept Med Informat, Rotterdam, Netherlands

来源：

MEDINFO 2010, PTS I AND II | 2010年 / 160卷

关键词：

Drug toxicity; Semantics; Medical records; Indexing; Information storage and retrieval; UMLS; MEDICAL LANGUAGE SYSTEM; TERMINOLOGY;

D O I：

10.3233/978-1-60750-588-4-1085

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

The overall objective of the EU-ADR project is the design, development, and validation of a computerised system that exploits data from electronic health records and biomedical databases for the early detection of adverse drug reactions. Eight different databases, containing health records of more than 30 million European citizens, are involved in the project. Unique queries cannot be performed across different databases because of their heterogeneity: Medical record and Claims databases, four different terminologies for coding diagnoses, and two languages for the information described in free text. The aim of our study was to provide database owners with a common basis for the construction of their queries. Using the UMLS, we provided a list of medical concepts, with their corresponding terms and codes in the four terminologies, which should be considered to retrieve the relevant information for the events of interest from the databases.

引用

页码：1085 / 1089

页数：5

共 6 条

[1] A Semantic Approach for the Homogeneous Identification of Events in Eight Patient Databases: A Contribution to the European eu-ADR Project
Avillach, Paul
Mougin, Fleur
Joubert, Michel
Thiessard, Frantz
Pariente, Antoine
Dufour, Jean-Charles
Trifiro, Gianluca
Polimeni, Giovanni
Catania, Maria Antonietta
Giaquinto, Carlo
Mazzaglia, Giampiero
Baio, Gianluca
Herings, Ron
Gini, Rosa
Hippisley-Cox, Julia
Molokhia, Mariam
Pedersen, Lars
Fourrier-Reglat, Annie
Sturkenboom, Miriam
Fieschi, Marius
[J]. MEDICAL INFORMATICS IN A UNITED AND HEALTHY EUROPE, 2009, 150 : 190 - 194
[2] Harmonization process for the identification of medical events in eight European healthcare databases: the experience from the EU-ADR project
Avillach, Paul
Coloma, Preciosa M.
Gini, Rosa
Schuemie, Martijn
Mougin, Fleur
Dufour, Jean-Charles
Mazzaglia, Giampiero
Giaquinto, Carlo
Fornari, Carla
Herings, Ron
Molokhia, Mariam
Pedersen, Lars
Fourrier-Reglat, Annie
Fieschi, Marius
Sturkenboom, Miriam
van der Lei, Johan
Pariente, Antoine
Trifiro, Gianluca
[J]. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, 2013, 20 (01) : 184 - 192
[3] Harmonization of the Event Identification Process in Eight European Healthcare Databases: The Experience from the EU-ADR Project
Trifiro', Gianluca
Avillach, Paul
Gini, Rosa
Coloma, Preciosa
Mazzaglia, Giampiero
Picelli, Gino
Scotti, Lorenza
Herings, Ron
Hippisley-Cox, Julia
Molokhia, Mariam
Pedersen, Lars
Reglat, Annie Fourrier
Pariente, Antoine
Sturkenboom, Miriam
van der Lei, Johan
[J]. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2011, 20 : S4 - S4
[4] HARMONISING DEFINITIONS OF ADVERSE EVENTS AMONG 8 EUROPEAN HEALTHCARE DATABASES PARTICIPATING IN THE EU-ADR PROJECT
Gini, R.
Avillach, P.
Coloma, P. M.
Mougin, F.
Dufour, J-C
Thiessard, F.
Joubert, M.
Mazzaglia, G.
Giaquinto, C.
Fornari, C.
Herings, R.
Hippisley-Cox, J.
Molokhia, M.
Pedersen, L.
Fourrier-Reglat, A.
Fieschi, M.
Sturkenboom, M.
Van Der Lei, J.
Pariente, A.
Trifiro, G.
[J]. EPIDEMIOLOGIA & PREVENZIONE, 2010, 34 (5-6): : 89 - 90
[5] A UMLS-Based Approach for the Homogeneous Identification of Events in Seven European Health Databases: A Contribution to the Safety of NSAIDs (SOS) Project
Thiessard, Frantz
Mougin, Fleur
Arfe, Andrea
Garbe, Edeltraut
Herings, Ron
Lucchi, Silvia
Nicotra, Federica
Picelli, Gino
Romio, Silvana
Schade, Rene
Schink, Tania
Straatman, Huub
Valkhoff, Vera E.
Villa, Marco
Fourrier, Annie
Sturkenboom, Miriam C. J. M.
[J]. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2011, 20 : S174 - S175
[6] Design and validation of an automated method to detect known adverse drug reactions in MEDLINE: a contribution from the EU-ADR project
Avillach, Paul
Dufour, Jean-Charles
Diallo, Gayo
Salvo, Francesco
Joubert, Michel
Thiessard, Frantz
Mougin, Fleur
Trifiro, Gianluca
Fourrier-Reglat, Annie
Pariente, Antoine
Fieschi, Marius
[J]. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, 2013, 20 (03) : 446 - 452

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