SOCS1 silencing can break high-dose dendritic cell immunotherapy-induced immune tolerance

被引：7
|
作者：
Hu, Qinghai [2 ]
Qin, Xia [2 ]
Qian, Gaochao [2 ]
Jiang, Shan [2 ]
Li, Haiyan [2 ]
Jiang, Min [1 ,2 ]
Li, Xiaoyan [2 ]
Chen, Si-Yi [3 ]
Zang, Ying Qin [1 ,2 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci, Shanghai 200031, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Med, Shanghai Inst Immunol, Shanghai 200025, Peoples R China
[3] Baylor Coll Med, Ctr Cell & Gene Therapy, Houston, TX 77030 USA
来源：
MOLECULAR MEDICINE REPORTS | 2008年 / 1卷 / 01期
关键词：
dendritic cell; immune tolerance; immunotherapy; SOCS1;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：61 / 70
页数：10
相关论文
共 45 条
  • [1] Can innate inflammatory factors break immunotherapy-induced T cell tolerance in patients with allergic asthma?
    Kucuksezer, U. C.
    Tahrali, I.
    Adin-Cinar, S.
    Gemicioglu, B.
    Akdis, A. C.
    Akdis, M.
    Deniz, G.
    IMMUNOLOGY, 2012, 137 : 440 - 440
  • [2] Suppressor of cytokine signaling 1 (SOCS1) silencing and Hep-2 sensitizing dendritic cell vaccine in laryngocarcinoma immunotherapy
    Yuan, Y.
    Li, G-Y
    Ji, M.
    Zhang, Y.
    Ding, Y-P
    Qi, X-C
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2019, 23 (13) : 5958 - 5966
  • [3] Defining control: Regulation of dendritic cell activation and immune homeostasis by SOCS1
    Starr, R
    Hilton, DJ
    IMMUNITY, 2003, 19 (03) : 308 - 309
  • [4] SOCS1 Attenuates the Ability of Dendritic Cells to Break Self-Tolerance and Induce Antitumor Immunity by Controlling Cytokine Production and Signaling
    Evel-Kabler, Kevin
    Chen, Si-Yi
    CANCER RESEARCH, 2006, 66 (08)
  • [5] SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling
    Evel-Kabler, K
    Song, XT
    Aldrich, M
    Huang, XF
    Chen, SY
    JOURNAL OF CLINICAL INVESTIGATION, 2006, 116 (01): : 90 - 100
  • [6] Silencing SOCS1 in dendritic cells promote survival of mice with systemic Candida albicans infection via inducing Th1-cell differentiation
    Shi, Dongmei
    Li, Dongmei
    Wang, Qiong
    Kong, Xue
    Mei, Huan
    Shen, Yongnian
    Liu, Weida
    IMMUNOLOGY LETTERS, 2018, 197 : 53 - 62
  • [7] Minocycline induces tolerance to dendritic cell production probably by targeting the SOCS1/ TLR4/NF-κB signaling pathway
    Han, Xu
    Wei, Qiao
    Xu, Rui-Xue
    Wang, Shi
    Liu, Xue-Yu
    Guo, Cong
    Gao, Qian
    Zhou, Xuan
    Chen, Li-Ping
    Li, Zhen-Fei
    TRANSPLANT IMMUNOLOGY, 2023, 79
  • [8] Defective Central Immune Tolerance Induced by High-Dose D-Galactose Resembles Aging
    H. M. Du
    Y. J. Wang
    X. Liu
    S. L. Wang
    S. M. Wu
    Z. Yuan
    X. K. Zhu
    Biochemistry (Moscow), 2019, 84 : 617 - 626
  • [9] Defective Central Immune Tolerance Induced by High-Dose D-Galactose Resembles Aging
    Du, H. M.
    Wang, Y. J.
    Liu, X.
    Wang, S. L.
    Wu, S. M.
    Yuan, Z.
    Zhu, X. K.
    BIOCHEMISTRY-MOSCOW, 2019, 84 (06) : 617 - 626
  • [10] Analysis of allogeneic hematopoietic stem cell transplantation with high-dose cyclophosphamide-induced immune tolerance for severe aplastic anemia
    Guo, Zhi
    Gao, Hong-yan
    Zhang, Tian-yan
    Liu, Xiao-dong
    Yang, Kai
    Lou, Jing-xing
    He, Xue-peng
    Zhang, Yuan
    Chen, Peng
    Chen, Hui-ren
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2016, 104 (06) : 720 - 728
12345