A water-soluble conjugated polymer with azobenzol side chains based on "turn-on" effect for hypoxic cell imaging

被引：14

作者：

Li, Jie ^{[1
,2
]}

Yuan, Yan ^{[3
,4
]}

Zeng, Gaoshan ^{[1
,2
]}

Li, Xiang ^{[1
,2
]}

Yang, Zhen ^{[1
,2
]}

Li, Xiaozhen ^{[1
,2
]}

Jiang, Rongcui ^{[1
,2
]}

Hu, Wenbo ^{[1
,2
]}

Sun, Pengfei ^{[1
,2
]}

Wang, Qi ^{[1
,2
]}

Lu, Xiaomei ^{[3
,4
]}

Fan, Quli ^{[1
,2
]}

Huang, Wei ^{[1
,2
,3
,4
]}

机构：

[1] Nanjing Univ Posts & Telecommun, KLOEID, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, 9 Wenyuan Rd, Nanjing 210023, Jiangsu, Peoples R China

[2] Nanjing Univ Posts & Telecommun, IAM, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, 9 Wenyuan Rd, Nanjing 210023, Jiangsu, Peoples R China

[3] Nanjing Tech Univ NanjingTech, Key Lab Flexible Elect KLOFE, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, 30 South Puzhu Rd, Nanjing 211816, Jiangsu, Peoples R China

[4] Nanjing Tech Univ NanjingTech, IAM, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, 30 South Puzhu Rd, Nanjing 211816, Jiangsu, Peoples R China

来源：

POLYMER CHEMISTRY | 2016年 / 7卷 / 45期

基金：

中国国家自然科学基金;

关键词：

FLUORESCENT-PROBES; ACTIVATION; DIAPHORASE; ENZYME; ASSAYS;

D O I：

10.1039/c6py01567k

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A water-soluble conjugated polymer (WSCP) with enzymatic cleavable linkages (azobenzene) side chains for hypoxia imaging is reported. The fluorescence of the polymer would be recovered as the azobenzene moieties cleaved in hypoxia. This conjugated polymer was proved to be a good hypoxic sensor.

引用

页码：6890 / 6894

页数：5

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