γ-Alumina Nanoparticle Catalyzed Efficient Synthesis of Highly Substituted Imidazoles

被引:12
|
作者
Reddy, Bandapalli Palakshi [1 ]
Vijayakumar, Vijayaparthasarathi [1 ]
Arasu, Mariadhas Valan [2 ]
Al-Dhabi, Naif Abdullah [2 ]
机构
[1] VIT Univ, Ctr Organ & Med Chem, Vellore 632014, Tamil Nadu, India
[2] King Saud Univ, Dept Bot & Microbiol, Addiriyah Chair Environm Studies, Dept Bot & Microbiol, Riyadh 11451, Saudi Arabia
关键词
benzil; arylaldehydes; gamma-Alumina NPs; one pot synthesis; 1,2,4,5-tetraaryl imidazoles; ONE-POT SYNTHESIS; SOLVENT-FREE SYNTHESIS; TETRASUBSTITUTED IMIDAZOLES; 1,2,4,5-TETRASUBSTITUTED IMIDAZOLES; MICROWAVE IRRADIATION; RECEPTOR ANTAGONISTS; INHIBITORS; ACID; SYSTEM; KINASE;
D O I
10.3390/molecules201019221
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
gamma-Alumina nano particle catalyzed multi component reaction of benzil, arylaldehyde and aryl amines afforded the highly substituted 1,2,4,5-tetraaryl imidazoles with good to excellent yield in less reaction time under the sonication as well as the conventional methods. Convenient operational simplicity, mild conditions and the reusability of catalyst were the other advantages of this developed protocol.
引用
收藏
页码:19221 / 19235
页数:15
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