Relationships among peripheral eosinophilia, eosinophil peroxidase activity, interleukin-5 concentration and faecal nematode egg count during natural, mixed gastrointestinal nematode infection

被引：16

作者：

Doligalska, M

Moskwa, B

Stear, MJ

机构：

[1] Univ Warsaw, Inst Zool, Dept Parasitol, PL-00927 Warsaw, Poland

[2] Polish Acad Sci, Witold Stefanski Inst Parasitol, PL-00818 Warsaw, Poland

[3] Univ Glasgow, Sch Vet, Dept Vet Clin Studies, Glasgow G61 1QH, Lanark, Scotland

来源：

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY | 1999年 / 70卷 / 3-4期

关键词：

nematode; sheep; eosinophil; peroxidase; interleukin-5; repeatability;

D O I：

10.1016/S0165-2427(99)00078-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A longitudinal study of sheep, naturally infected with gastrointestinal helminths, was carried out to quantify the relationships among eosinophilia, eosinophil peroxidase activity, interleukin-5 level and faecal egg counts. Faecal egg counts, peripheral eosinophilia and peroxidase activity per eosinophil were moderately repeatable but interleukin-5 concentrations had a remarkably high repeatability. Animals with higher concentrations of interleukin-5 had greater peripheral eosinophilia and those animals with higher numbers of eosinophils had lower faecal egg counts. These associations were statistically significant but quite weak. Variation in interleukin-5 levels does not appear to be responsible for most of the variation in eosinophil responses in outbred sheep. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：299 / 308

页数：10