PathVisio-Faceted Search: an exploration tool for multi-dimensional navigation of large pathways

被引:3
|
作者
Fried, Jake Y. [1 ]
van Iersel, Martijn P. [2 ]
Aladjem, Mirit I. [3 ]
Kohn, Kurt W. [3 ]
Luna, Augustin [3 ,4 ]
机构
[1] Univ Maryland, College Pk, MD 20740 USA
[2] Gen Bioinformat Ltd, Reading RG4 7RT, Berks, England
[3] NCI, Mol Pharmacol Lab, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
[4] Boston Univ, Bioinformat Program, Boston, MA 02215 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1093/bioinformatics/btt146
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Purpose: The PathVisio-Faceted Search plugin helps users explore and understand complex pathways by overlaying experimental data and data from webservices, such as Ensembl BioMart, onto diagrams drawn using formalized notations in PathVisio. The plugin then provides a filtering mechanism, known as a faceted search, to find and highlight diagram nodes (e. g. genes and proteins) of interest based on imported data. The tool additionally provides a flexible scripting mechanism to handle complex queries.
引用
收藏
页码:1465 / 1466
页数:2
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