Bioactive metabolites from a marine-derived strain of the fungus Neosartorya fischeri

被引：28
|
作者：
Tan, Qing-Wei [1 ]
Ouyang, Ming-An [1 ]
Shen, Shuo [2 ]
Li, Wei [2 ]
机构：
[1] Fujian Agr & Forestry Univ, Inst Plant Virol, Fuzhou 350002, Fujian, Peoples R China
[2] Qinghai Acad Agr & Forestry, Inst Biotechnol, Xining 810016, Qinghai, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2012年 / 26卷 / 15期
关键词：
Neosartorya fischeri; fischeacid; fischexanthone; cytotoxicity; antiphytoviral effect; GROWTH; IDENTIFICATION;
D O I：
10.1080/14786419.2011.592834
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new compounds named fischeacid (1) and fischexanthone (2), together with eight known compounds, were obtained from the culture of a marine-derived fungus Neosartorya fischeri strain 1008F(1). The structures of the new compounds were elucidated based on the spectroscopic data. Bioassays indicated that AGI-B4 (5) and 3,4-dihydroxybenzoic acid (10) showed potent inhibitory effect on the replication of tobacco mosaic virus, and AGI-B4 also possessed an inhibition of the cell proliferation of human gastric cancer cell line SGC-7901 and hepatic cancer cells BEL-7404.
引用
收藏
页码：1402 / 1407
页数：6
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