The aim of this prospective, adult population-based study was to analyse the prevalence of type 2 diabetes mellitus in relation to the intake of cows' milk and the prevalence of anti-beta-lactoglobulin (anti-beta-LG) antibodies. Measurements were made of weight, height, levels of anti-islet antibodies, anti-beta-LG antibodies and tumour necrosis factor alpha (TNF-alpha) in all the participants. The likelihood of having positive anti-beta-LG antibodies was higher in subjects who consumed milk more frequently. Subjects who consumed milk less than once per day were more likely to have type 2 diabetes than those who consumed milk more than once per day. The levels of TNF-alpha were significantly higher in individuals with positive anti-beta-LG antibodies and in those who consumed milk more often. The prevalence of anti-beta-LG antibodies was associated with the intake of milk and with the TNF-alpha levels, but not with the prevalence of type 2 diabetes. (C) 2012 Elsevier Ltd. All rights reserved.
机构:
Chengdu Med Coll, Dept Gynaecol, Affiliated Hosp 1, Chengdu, Peoples R ChinaChengdu Med Coll, Dept Gynaecol, Affiliated Hosp 1, Chengdu, Peoples R China
Lu, Ling
Ma, Yan
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Chengdu Med Coll, Dept Obstet, Affiliated Hosp 1, Chengdu, Peoples R ChinaChengdu Med Coll, Dept Gynaecol, Affiliated Hosp 1, Chengdu, Peoples R China
Ma, Yan
Deng, Jie
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Chengdu Med Coll, Dept Gynaecol, Affiliated Hosp 1, Chengdu, Peoples R ChinaChengdu Med Coll, Dept Gynaecol, Affiliated Hosp 1, Chengdu, Peoples R China
Deng, Jie
Xie, Jiaqiong
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Chengdu Med Coll, Dept Gynaecol, Affiliated Hosp 1, Chengdu, Peoples R ChinaChengdu Med Coll, Dept Gynaecol, Affiliated Hosp 1, Chengdu, Peoples R China
Xie, Jiaqiong
Huang, Chaolin
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Chengdu Med Coll, Dept Gynaecol, Affiliated Hosp 1, Chengdu, Peoples R ChinaChengdu Med Coll, Dept Gynaecol, Affiliated Hosp 1, Chengdu, Peoples R China
Huang, Chaolin
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