The synthesis of novel amino acids via hydroboration-Suzuki cross coupling

被引:30
|
作者
Campbell, AD
Raynham, TM
Taylor, RJK [1 ]
机构
[1] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England
[2] Roche Discovery Welwyn, Welwyn Garden City AL7 3AY, Herts, England
关键词
D O I
10.1016/S0040-4039(99)00997-1
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The Garner aldehyde-derived methylene alkene has been hydroborated using 9-BBN and the resulting organoborane employed in palladium-catalysed Suzuki coupling reactions to produce, after hydrolysis-oxidation, a range of novel amino acids as their N-BOC protected derivatives. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:5263 / 5266
页数:4
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