Piezoelectric peristaltic micropump integrated on a microfluidic chip

被引:73
|
作者
Ma, Tuo [1 ]
Sun, Shixin [1 ]
Li, Baoqing [1 ]
Chu, Jiaru [1 ]
机构
[1] Univ Sci & Technol China, Dept Precis Machinery & Precis Instrumentat, Hefei 230027, Anhui, Peoples R China
基金
中国国家自然科学基金;
关键词
Micropump; Microfluidic chip; Micro mixing; MICROVALVES; VALVES;
D O I
10.1016/j.sna.2019.04.005
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Micropump is extremely useful in miniature biochemical analysis systems for its abilities of manipulating and transporting minute liquid. We developed a novel peristaltic micropump to pump fluids in microfluidic chip in this article. The micropump consists of three piezoelectric actuators, and part of a microfluidic chip as a compressible microchannel. The fluid in the microchannel is transported owning to a series of impacting actions on the microchannel by the piezoelectric actuators. The microchannel is integrated fabricated with the microfluidic chip, which ensures a tiny dead volume less than 300 nL. Being beneficial from the plug-and-play design of the microfluidic chip, there is no cross-contamination for the reagent has no contact with the reusable actuators. Calibration shows the micropump can transport liquid at a high resolution of 8.4 nL/s, a maximum flow rate of 102 nL/s, and backpressure of up to 2.0 K Pa. A demonstration of mixing liquids on a chip was carried out using two micropumps, indicating its great potential for manipulating microamount reagent in biochemical application. (C) 2019 Elsevier B.V. All rights reserved.
引用
收藏
页码:90 / 96
页数:7
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