Chemical composition and biological potential of Thymus Willdenowii Boiss. & Reut. essential oil

被引：7
|
作者：
Zeghib, Assia [1 ]
Calliste, Claude-Alain [2 ]
Simon, Alain [3 ]
Charfeddine, Rim [4 ]
Aouni, Mahjoub [4 ]
Duroux, Jean-Luc [2 ]
Kabouche, Ahmed [1 ]
Kabouche, Zahia [1 ]
机构：
[1] Univ Freres Mentouri Constantine 1, LOST, Dept Chim, Constantine 25000, Algeria
[2] Univ Limoges, Inst GEIST, Lab Biophys, Fac Pharm,EA LCSN 1069, Limoges, France
[3] Univ Limoges, Inst GEIST, Lab Chim Phys & Minerale, Fac Pharm,EA LCSN 1069, Limoges, France
[4] Univ Monastir, Fac Pharm, Lab Malad Transmissibles & Subst Biologiquement A, Monastir, Tunisia
来源：
NATURAL PRODUCT RESEARCH | 2021年 / 35卷 / 05期
关键词：
Thymus willdenowii Boiss & Reut; essential oil; cytotoxicity; antibacterial; antiproliferative; antioxidant; antiviral; ANTIOXIDANT;
D O I：
10.1080/14786419.2019.1602830
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The fresh aerial parts of Thymus willdenowii Boiss. & Reut. (syn. Thymus hirtus Willd.) were hydrodistilled in a Clevenger type apparatus and analyzed by GC and GC-MS. 44 Components were identified representing 97.3%, with 1,8-cineole (34.62%), camphor (18.55%), alpha-pinene (9.46%) and camphene (5.38%) as the main components. T. willdenowii essential oil was not cytotoxic (CC50 = 97.65 mu g/mL) towards Vero non-tumoural cells, exhibiting good antibacterial and antiproliferative (30.8 +/- 3.1% inhibition) potentials against four tested pathogenic bacteria and Human colorectal cell line HT-29, respectively. The essential oil did not show a DPPH radical scavenging activity, by Electron Spin Resonance spectroscopy (ESR), and it lacks antiviral effect towards coxsackievirus B3. [GRAPHICS] .
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收藏
页码：845 / 848
页数：4
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