Role of β-Adrenergic Receptors and Nitric Oxide Signaling in Exercise-Mediated Cardioprotection

被引：37
|
作者：
Calvert, John W. [1 ]
Lefer, David J. [1 ]
机构：
[1] Emory Univ, Sch Med, Div Cardiothorac Surg, Dept Surg,Carlyle Fraser Heart Ctr, Atlanta, GA 30322 USA
来源：
PHYSIOLOGY | 2013年 / 28卷 / 04期
关键词：
ISCHEMIA-REPERFUSION INJURY; MITOCHONDRIAL PERMEABILITY TRANSITION; ACUTE MYOCARDIAL-INFARCTION; ACTIVATED PROTEIN-KINASE; ENDOTHELIAL NO SYNTHASE; K-ATP CHANNEL; PHYSICAL-ACTIVITY; ISCHEMIA/REPERFUSION INJURY; S-NITROSYLATION; GENE-EXPRESSION;
D O I：
10.1152/physiol.00011.2013
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Exercise promotes cardioprotection in both humans and animals not only by reducing risk factors associated with cardiovascular disease but by reducing myocardial infarction and improving survival following ischemia. This article will define the role that nitric oxide and beta-adrenergic receptors play in mediating the cardioprotective effects of exercise in the setting of ischemia-reperfusion injury.
引用
收藏
页码：216 / 224
页数：9
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