Sorafenib: the gold standard therapy in advanced hepatocellular carcinoma and beyond

被引:19
|
作者
Gadaleta-Caldarola, Gennaro [1 ]
Divella, Rosa [2 ]
Mazzocca, Antonio [3 ,4 ]
Infusino, Stefania [5 ]
Ferraro, Emanuela [6 ]
Filippelli, Gianfranco [5 ]
Daniele, Antonella [2 ]
Sabba, Carlo [3 ]
Abbate, Ines [2 ]
Brandi, Mario [1 ]
机构
[1] Mons R Dimiccoli Hosp, Div Oncol, I-76121 Barletta Bt, Asl Bat, Italy
[2] Ist Tumori Giovanni Paolo II, Natl Canc Res Ctr, Clin Pathol Lab, I-70100 Bari, Italy
[3] Univ Bari, Sch Med, Interdisciplinary Dept Med, I-70124 Bari, Italy
[4] IRCCS Saverio De Bellis, Natl Inst Digest Dis, I-70013 Bari, Italy
[5] S Francesco di Paola Hosp, Div Oncol, I-87027 Paola Cs, ASP, Italy
[6] Univ Roma La Sapienza, Policlin Umberto 1, Dept Internal Med & Clin Specialties, I-00161 Rome, Italy
关键词
HCC; multikinase inhibitors; RAS; RAF; MEK; ERK pathway; sorafenib; PHASE-III TRIAL; RAF/MEK/ERK PATHWAY; ANGIOGENESIS; TARGETS;
D O I
10.2217/fon.15.161
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:2263 / 2266
页数:4
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