A context-aware approach for progression tracking of medical concepts in electronic medical records

被引:25
|
作者
Chang, Nai-Wen [1 ,2 ]
Dai, Hong-Jie [3 ]
Jonnagaddala, Jitendra [4 ]
Chen, Chih-Wei [5 ]
Tsai, Richard Tzong-Han [6 ]
Hsu, Wen-Lian [1 ]
机构
[1] Acad Sinica, Inst Informat Sci, Taipei, Taiwan
[2] Natl Taiwan Univ, Grad Inst Biomed Elect & Bioinformat, Taipei, Taiwan
[3] Natl Taitung Univ, Dept Comp Sci & Informat Engn, Taitung, Taiwan
[4] Univ New South Wales, Sch Publ Hlth & Community Med, Sydney, NSW, Australia
[5] Taipei Med Univ, Coll Med Sci & Technol, Grad Inst Biomed Informat, Taipei, Taiwan
[6] Natl Cent Univ, Dept Comp Sci & Informat Engn, Taoyuan, Taiwan
关键词
Clinical natural language processing; Temporal information extraction; Electronic medical record;
D O I
10.1016/j.jbi.2015.09.013
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Electronic medical records (EMRs) for diabetic patients contain information about heart disease risk factors such as high blood pressure, cholesterol levels, and smoking status. Discovering the described risk factors and tracking their progression over time may support medical personnel in making clinical decisions, as well as facilitate data modeling and biomedical research. Such highly patient-specific knowledge is essential to driving the advancement of evidence-based practice, and can also help improve personalized medicine and care. One general approach for tracking the progression of diseases and their risk factors described in EMRs is to first recognize all temporal expressions, and then assign each of them to the nearest target medical concept. However, this method may not always provide the correct associations. In light of this, this work introduces a context-aware approach to assign the time attributes of the recognized risk factors by reconstructing contexts that contain more reliable temporal expressions. The evaluation results on the i2b2 test set demonstrate the efficacy of the proposed approach, which achieved an F-score of 0.897. To boost the approach's ability to process unstructured clinical text and to allow for the reproduction of the demonstrated results, a set of developed .NET libraries used to develop the system is available at https://sites.google.com/site/hongjiedai/projects/nttmuclinicalnet. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:S150 / S157
页数:8
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