Development of a Collagen Hydrogel with High Mechanical Strength by a Simple Orientation Method for Triple-helix

被引：5
|
作者：
Hongo, Chizuru [1 ,2 ]
Matsusaki, Michiya [1 ,2 ]
Nishida, Kohji [2 ,3 ]
Akashi, Mitsuru [1 ,2 ]
机构：
[1] Osaka Univ, Grad Sch Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan
[2] Osaka Univ, 21st Century COE Program, Ctr Integrated Cell & Tissue Regulat, Suita, Osaka 5650871, Japan
[3] Tohoku Univ, Sch Med, Dept Ophthalmol, Aoba Ku, Sendai, Miyagi 9808574, Japan
来源：
CHEMISTRY LETTERS | 2008年 / 37卷 / 12期
关键词：
D O I：
10.1246/cl.2008.1254
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Collagen hydrogels with oriented triple-helix were fabricated simply via the axial orientation of a dense collagen solution onto a glass plate and cross-linking. The orientation of the collagen triple-helix in the gels was clearly confirmed by X-ray diffraction measurements. The tensile strength of the oriented collagen gels in parallel was twofold higher than that of non-oriented gels as a control. Our collagen gels with oriented triple-helix can be. useful as novel scaffolds in the tissue engineering field.
引用
收藏
页码：1254 / 1255
页数：2
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