Lewis Acid Catalyzed SN2-Type Ring Opening of N-Activated Aziridines with Electron-Rich Arenes/Heteroarenes

被引：53
|
作者：
Ghorai, Manas K. [1 ]
Tiwari, Deo Prakash [1 ]
Jain, Nikita [1 ]
机构：
[1] Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 78卷 / 14期
关键词：
ENANTIOSELECTIVE SYNTHESIS; MESO-AZIRIDINES; C-ARYLATION; STEREOCONTROLLED SYNTHESIS; CYCLIZATION REACTIONS; EFFICIENT CATALYST; TOSYL AZIRIDINES; SYNTHETIC ROUTE; DERIVATIVES; TRANSFORMATION;
D O I：
10.1021/jo401028j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient Lewis acid catalyzed S(N)2-type ring opening of substituted aziridines with electron-rich arenes/heteroarenes to provide substituted 2,2-diaryl/heteroarylethylamines in excellent yields and stereoselectivity (er, dr >99:1) is described.
引用
收藏
页码：7121 / 7130
页数：10
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