A novel Sarcocystis-associated encephalitis and myositis in racing pigeons

被引:38
|
作者
Olias, P. [1 ]
Gruber, A. D. [1 ]
Heydorn, A. O. [2 ]
Kohls, A. [3 ]
Mehlhorn, H. [4 ]
Hafez, H. M. [3 ]
Lierz, M. [3 ]
机构
[1] Free Univ Berlin, Dept Vet Pathol, D-14163 Berlin, Germany
[2] Free Univ Berlin, Inst Vet Parasitol, D-14163 Berlin, Germany
[3] Free Univ Berlin, Inst Poultry Dis, D-14163 Berlin, Germany
[4] Univ Dusseldorf, Dept Zoomorphol Cytol & Parasitol, D-40225 Dusseldorf, Germany
关键词
EXPERIMENTAL TRANSMISSION; FALCATULA STILES; NEURONA; INFECTIONS; BIRDS; MENINGOENCEPHALITIS; FRENKELIA; PATHOLOGY; CANARIES; PARASITE;
D O I
10.1080/03079450902737847
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Sarcosporidian cysts in the skeletal muscle of domestic pigeons (Columba livia f. domestica) have previously been attributed to infection with Sarcocystis falcatula, which is shed in the faeces of the opossum (Didelphis virginiana). Here, we describe fatal spontaneous encephalitis and myositis associated with Sarcocystis infections in three flocks of racing pigeons with 47 of 244 animals affected. The clinical course was characterized by depression, mild diarrhoea, torticollis, opisthotonus, paralysis and trembling. Histopathological examination of 13 pigeons revealed generalized severe granulomatous and necrotizing meningoencephalitis and myositis with sarcosporidian cysts. Light and transmission electron microscopy identified cysts in heart and skeletal muscle of 1 to 2 mm in length and 20 to 50 m in width. These were subdivided into small chambers by fine septae and filled with lancet-shaped cystozoites (7.51.5 m) and dividing metrocytes, which is characteristic for Sarcocystis. The cysts had smooth walls and were devoid of protrusions typical of S. falcatula. Polymerase chain reaction amplification and sequencing of the internal transcribed spacer region (ITS-1) and the complete 28S rRNA identified a novel Sarcocystis species with only 51% ITS-1 nucleotide sequence similarity with S. falcatula. A phylogenetic comparison of the 28S rRNA revealed close sequence homologies with Frenkelia microti, Frenkelia glareoli and Sarcocystis neurona. The clinical, histopathological, electron microscopic and genetic data are unlike any previously described protozoan infections in pigeons, suggesting a novel, severe disease due to an as yet undescribed Sarcocystis species.
引用
收藏
页码:121 / 128
页数:8
相关论文
共 50 条
  • [1] EMERGENCE OF A NOVEL SARCOCYSTIS-ASSOCIATED ENCEPHALITIS AND MYOSITIS IN DOMESTIC PIGEONS TRANSMITTED BY THE NORTHERN GOSHAWK
    Olias, P.
    Lierz, M.
    Hafez, H. M.
    Heydorn, A. O.
    Kohls, A.
    Mehlhorn, H.
    Gruber, A. D.
    [J]. JOURNAL OF COMPARATIVE PATHOLOGY, 2009, 141 (04) : 266 - 266
  • [2] SARCOCYSTIS-ASSOCIATED ENCEPHALITIS IN CHICKENS
    MUTALIB, A
    KEIRS, R
    MASLIN, W
    TOPPER, M
    DUBEY, JP
    [J]. AVIAN DISEASES, 1995, 39 (02) : 436 - 440
  • [3] Sarcocystis-associated encephalitis and myocarditis in a wild turkey (Meleagris gallopavo)
    Teglas, MB
    Little, SE
    Latimer, KS
    Dubey, JP
    [J]. JOURNAL OF PARASITOLOGY, 1998, 84 (03) : 661 - 663
  • [4] SARCOCYSTIS-ASSOCIATED MENINGOENCEPHALOMYELITIS IN A CAT
    DUBEY, JP
    HIGGINS, RJ
    BARR, BC
    SPANGLER, WL
    KOLLIN, B
    JORGENSEN, LS
    [J]. JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 1994, 6 (01) : 118 - 120
  • [5] SARCOCYSTIS-ASSOCIATED ENCEPHALITIS IN AN IMMATURE NORTHERN GOSHAWK (ACCIPITER-GENTILIS-ATRICAPILLUS)
    AGUILAR, RF
    SHAW, DP
    DUBEY, JP
    REDIG, P
    [J]. JOURNAL OF ZOO AND WILDLIFE MEDICINE, 1991, 22 (04) : 466 - 469
  • [6] MULTIFOCAL MYOSITIS ASSOCIATED WITH SARCOCYSTIS SP IN A HORSE
    TRAUBDARGATZ, JL
    SCHLIPF, JW
    GRANSTROM, DE
    INGRAM, JT
    SHELTON, GD
    GETZY, DM
    LAPPIN, MR
    BAKER, DC
    [J]. JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 1994, 205 (11) : 1574 - 1576
  • [7] Sarcocystis giganteainfection associated with granulomatous eosinophilic myositis in a horse
    Veronesi, Fabrizia
    Di Palma, Stefano
    Gabrielli, Simona
    Morganti, Giulia
    Milardi, Giovanni L.
    Middleton, Bruce
    Lepri, Elvio
    [J]. JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 2020, 32 (04) : 611 - 615
  • [8] Sarcocystis capracanis-associated encephalitis in sheep
    Beard, P. M.
    [J]. VETERINARY PARASITOLOGY, 2013, 197 (1-2) : 409 - 409
  • [9] INCLUSION BODY HEPATITIS ASSOCIATED WITH AN ADENOVIRUS IN RACING PIGEONS IN AUSTRALIA
    KETTERER, PJ
    TIMMINS, BJ
    PRIOR, HC
    DINGLE, JG
    [J]. AUSTRALIAN VETERINARY JOURNAL, 1992, 69 (04) : 90 - 91
  • [10] Natural Occurring Muscular Sarcocysts in Urban Domestic Cats (Felis catus) Without Sarcocystis-Associated Disease
    Bruna Marquardt Lucio
    Camila Encarnação Minuzzi
    Nícolas Carmo de Avila
    Luís Antonio Scalabrin Tondo
    Fernanda Silveira Flores Vogel
    Glaucia Denise Kommers
    Fagner D’ambroso Fernandes
    Clândio Timm Marques
    Mariana Martins Flores
    [J]. Acta Parasitologica, 2021, 66 : 129 - 135