Neuropeptides as lung cancer growth factors

被引:18
|
作者
Moody, Terry W. [1 ]
Moreno, Paola [2 ]
Jensen, Robert T. [2 ]
机构
[1] NCI, US Dept HHS, Ctr Canc Res, Off Director, Bethesda, MD 20892 USA
[2] NIDDK, Digest Dis Branch, Bethesda, MD 20892 USA
关键词
Lung cancer; Bombesin; Vasoactive intestinal peptide; Neurotensin; GASTRIN-RELEASING-PEPTIDE; VASOACTIVE-INTESTINAL-PEPTIDE; CAUSES TYROSINE PHOSPHORYLATION; BOMBESIN-LIKE PEPTIDES; FACTOR RECEPTOR; CYTOSOLIC CALCIUM; EGF-RECEPTOR; MAP-KINASE; NEUROTENSIN; POLYPEPTIDE;
D O I
10.1016/j.peptides.2015.03.018
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This manuscript is written in honor of the Festschrift for Abba Kastin. I met Abba at a Society for Neuroscience meeting and learned that he was Editor-in-Chief of the Journal Peptides. I submitted manuscripts to the journal on "Neuropeptides as Growth Factors in Cancer" and subsequently was named to the Editorial Advisory Board. Over the past 30 years I have published dozens of manuscripts in Peptides and reviewed hundreds of submitted manuscripts. It was always rewarding to interact with Abba, a consummate professional. When I attended meetings in New Orleans I would sometimes go out to dinner with him at the restaurant "Commanders Palace". When I chaired the Summer Neuropeptide Conference we were honored to have him receive the Fleur Strand Award one year in Israel. I think that his biggest editorial contribution has been the "Handbook of Biologically Active Peptides." I served as a Section Editor on "Cancer/Anticancer Peptides" and again found that it was a pleasure working with him. This review focuses on the mechanisms by which bombesin-like peptides, neurotensin and vasoactive intestinal peptide regulate the growth of lung cancer. Published by Elsevier Inc.
引用
收藏
页码:106 / 111
页数:6
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