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Harvard Univ, Dept Obstet & Gynecol & Reprod Biol, Div Reprod Endocrinol & Infertil, Beth Israel Deaconess Med Ctr,Sch Med,Boston IVF, Boston, MA 02215 USA Harvard Univ, Dept Obstet & Gynecol & Reprod Biol, Div Reprod Endocrinol & Infertil, Beth Israel Deaconess Med Ctr,Sch Med,Boston IVF, Boston, MA 02215 USA