Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review

被引：117
|
作者：
Steglich, Patrick [1 ,2 ]
Huelsemann, Marcel [3 ]
Dietzel, Birgit [2 ]
Mai, Andreas [1 ,2 ]
机构：
[1] IHP Leibniz Inst Innovat Mikroelekt, Technol Pk 25, D-15236 Frankfurt, Oder, Germany
[2] Tech Hsch Wildau, Hochschulring 1, D-15745 Wildau, Germany
[3] First Sensor AG, Peter Behrens Str 15, D-12459 Berlin, Germany
来源：
MOLECULES | 2019年 / 24卷 / 03期
关键词：
biosensors; biophotonics; integrated optical sensors; aptamers; biomaterials; optical sensor; silicon photonics; ring resonators; lab-on-a-chip; PHOTONIC MICRORING RESONATORS; WAVE-GUIDE; HIGH-SENSITIVITY; AFLATOXIN M-1; LABEL-FREE; ENHANCED SENSITIVITY; TEMPERATURE SENSOR; PASTEURIZED MILK; INTEGRATION; PERFORMANCE;
D O I：
10.3390/molecules24030519
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent developments in optical biosensors based on integrated photonic devices are reviewed with a special emphasis on silicon-on-insulator ring resonators. The review is mainly devoted to the following aspects: (1) Principles of sensing mechanism, (2) sensor design, (3) biofunctionalization procedures for specific molecule detection and (4) system integration and measurement set-ups. The inherent challenges of implementing photonics-based biosensors to meet specific requirements of applications in medicine, food analysis, and environmental monitoring are discussed.
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页数：16
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