The relationship between sodium, potassium, and hypothyroidism in Chronic Kidney Disease (CKD) patients

Introduction: The thyroid hormone itself carries out a variety of metabolic functions including the regulation of lipids, carbohydrates, proteins and electrolytes, and mineral metabolism, which will affect electrolyte balance. The objective of this study was to look at the relationship between sodium and potassium, and hypothyroidism. Methods: A cross-sectional study on subject data were taken retrospectively by looking at medical records of patients treated at Dr. Kariadi Hospital Semarang from 1 June 2017 to 1 June 2018 to see the relationship between serum sodium and potassium, and hypothyroidism. Results: Sodium did not show significant correlation with thyroidstimulating hormone (TSH) and thyroxine (T4) (p = .985 and p = .705). Correlation test between potassium and urea showed a significant relationship (p = .005 and r = .441). Likewise, regarding the relationship with creatinine, sodium did not show a significant correlation (p = .890 and r = .023), while potassium showed significant correlation (p = .003 and r = .466). Conclusions: There was no significant relationship between serum sodium and potassium and thyroid hormone (TSH and T4). There is a significant positive correlation between ureum creatinine and potassium.