Uneven and combined development. Regional Studies. The concept of uneven and combined development (U&CD) interprets dynamic historical change and comparative geographical differentiation in terms of the co-existence of tendencies towards differentiation and equalization of the conditions of production, consumption, distribution and exchange, deriving from capital accumulation and political multiplicity. U&CD entails a conception of the global system as a constellation of interdependent, national institutional configurations and interests that shape international/national/regional trends. To explain geographies of industrialization and urbanization and current trends towards a pluri-centric world, U&CD requires, however, a specification of the underlying causal mechanisms, examined in economic geography, international relations and developmental state theories.