Immunomodulatory activity of alcoholic extract of Mangifera indica L. in mice

被引：144
|
作者：
Makare, N [1 ]
Bodhankar, S [1 ]
Rangari, V [1 ]
机构：
[1] Bharati Vidyapeeth Deemed Univ, Poona Coll Pharm, Pune 411038, Maharashtra, India
来源：
JOURNAL OF ETHNOPHARMACOLOGY | 2001年 / 78卷 / 2-3期
关键词：
Mangifera indica; Cell mediated immunity; humoral immunity; immunomodulatory;
D O I：
10.1016/S0378-8741(01)00326-9
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Mangifera indica Linn, a plant widely used in the traditional medicinal systems of India, has been reported to possess antiviral, antibacterial and anti-inflammatory activities. In the present study, the alcoholic extract of stem bark of Mangifera indica Linn (Extract I containing mangiferin 2.6%), has been investigated for its effect on cell mediated and humoral components of the immune system in mice. Administration of test extract I produced increase in humoral antibody (HA) titre and delayed type hypersensitivity (DTH) in mice. It is concluded that test extract I is a promising drug with immunostimulant properties. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：133 / 137
页数：5
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