Italian Clinical Practice Guidelines on Cholangiocarcinoma - Part II: Treatment

被引：43

作者：

Alvaro, Domenico ^{[1
]}

Hassan, Cesare ^{[2
]}

Cardinale, Vincenzo ^{[3
]}

Carpino, Guido ^{[4
]}

Fabris, Luca ^{[5
]}

Gringeri, Enrico ^{[6
]}

Granata, Vincenza ^{[7
]}

Mutignani, Massimiliano ^{[8
]}

Morement, Helen ^{[9
]}

Giuliante, Felice ^{[10
]}

Guglielmi, Alfredo ^{[11
]}

Ridola, Lorenzo ^{[1
]}

Tonini, Giuseppe ^{[12
]}

Marzioni, Marco ^{[13
]}

Grazi, Gianluca ^{[14
]}

Guido, Maria ^{[15
]}

Di Giulio, Emilio ^{[16
]}

Pantano, Francesco ^{[12
]}

Venere, Rosanna ^{[1
]}

Bragazzi, Maria Consiglia ^{[17
]}

Biancanello, Francesca ^{[3
]}

Faccioli, Jessica ^{[1
]}

Giannetti, Aurora ^{[8
]}

Cintolo, Marcello ^{[8
]}

Di Giunta, Michela ^{[6
]}

Gambato, Martina ^{[18
,19
]}

Lasagni, Alberto ^{[5
]}

Izzo, Francesco ^{[20
]}

Avallone, Antonio ^{[21
]}

Banales, Jesus ^{[22
]}

Rossi, Massimo ^{[23
]}

Catalano, Carlo ^{[24
]}

Laghi, Andrea ^{[16
]}

D'Amati, Giulia ^{[25
]}

Mancino, Maria Grazia ^{[26
]}

机构：

[1] Sapienza Univ Rome, Dept Translat & Precis Med, Rome, Italy

[2] Nuovo Regina Margherita Hosp, Gastroenterol Unit, Rome, Italy

[3] Sapienza Univ Rome, Dept Med Surg Sci & Biotechnol, Rome, Italy

[4] Univ Rome Foro Italico, Div Hlth Sci, Dept Movement Human & Hlth Sci, Rome, Italy

[5] Azienda Osped Univ Padova, Dept Mol Med, Padua, Italy

[6] DISCOG, Dept Surg Oncol & Gastroenterol, Hepatobiliary Surg & Liver Transplantat Unit, Padua, Italy

[7] Fdn Pascale, IRCCS, Ist Nazl Tumori, Div Radiol, Naples, Italy

[8] ASST Niguarda, Digest Endoscopy Unit, Milan, Italy

[9] AMMF Cholangiocarcinoma Char, London, England

[10] Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli IRCCS, Unit Hepatobiliary Surg, Rome, Italy

[11] Univ Verona, GB Rossi Univ Hosp, Dept Surg, Div Gen & Hepatobiliary Surg, Verona, Italy

[12] Univ Campus Biomed, Dept Med Oncol, Rome, Italy

[13] Univ Politecn Marche, Dept Gastroenterol & Hepatol, Ancona, Italy

[14] IRCCS Regina Elena Natl Canc Inst, Dept Surg, Div Hepatopancreatobiliary Surg, Rome, Italy

[15] Univ Padua, Dept Med DIMED, Padua, Italy

[16] Sapienza Univ Rome, Dept Med Surg Sci & Translat Med, Rome, Italy

[17] Santa Maria Goretti Hosp, Gastroenterol Unit, Latina, Italy

[18] DISCOG, Multivisceral Transplant Unit, Padua, Italy

[19] DISCOG, Dept Surg Oncol & Gastroenterol, Gastroenterol, Padua, Italy

[20] Fdn Pascale, IRCCS, Ist Nazl Tumori, Div Hepatobiliary Surg, Naples, Italy

[21] Fdn Pascale, IRCCS, Ist Nazl Tumori, Div Abdominal Oncol, Naples, Italy

[22] Univ Basque Country UPV EHU, Dept Liver & Gastrointestinal Dis, Biodonostia Res Inst, Donostia Univ Hosp, San Sebastian, Spain

[23] Sapienza Univ Rome, Dept Surg, Hepatobiliopancreat & Liver Transplant Unit, Rome, Italy

[24] Sapienza Univ Rome, Dept Radiol Oncol & Anatomopathol Sci, Rome, Italy

[25] Sapienza Univ Rome, Dept Radiol Oncol & Pathol Sci, Rome, Italy

[26] AORN St Anna & San Sebastiano, UOC Gastroenterol & Endoscopia Digest, Caserta, Italy

来源：

DIGESTIVE AND LIVER DISEASE | 2020年 / 52卷 / 12期

关键词：

Intrahepatic cholangiocarcinoma; Perihilar cholangiocarcinoma; Distal cholangiocarcinoma; Target therapies; Locoregional treatments; Surgery; Liver transplantation; PREOPERATIVE BILIARY DRAINAGE; STEREOTACTIC BODY RADIOTHERAPY; PORTAL-VEIN EMBOLIZATION; UNRESECTABLE INTRAHEPATIC CHOLANGIOCARCINOMA; POSITRON-EMISSION-TOMOGRAPHY; INTERNAL RADIATION-THERAPY; LONG-TERM SURVIVAL; HILAR CHOLANGIOCARCINOMA; LIVER-TRANSPLANTATION; STAGING LAPAROSCOPY;

D O I：

10.1016/j.dld.2020.08.030

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Currently, the only curative treatment for cholangiocarcinoma (CCA) is surgical resection, though this treatment is possible in less than 40% of patients. However, recent improvements in preoperative management have led to a higher number of patients who are candidates for this procedure. For unresectable patients, progress is ongoing in terms of locoregional and chemoradiation treatments and target therapies, especially in the definition of patient selection criteria. This is the second part of the Italian CCA guidelines, dealing with CCA treatment, that have been formulated in accordance with Italian National Institute of Health indications and developed according to the GRADE method and related advancements. (C) 2020 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

引用

页码：1430 / 1442

页数：13

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