The utility of whole-body diffusion-weighted MRI for delineating regions of interest in PET

被引：3
|
作者：
Blackledge, M. D. [1 ,2 ,3 ]
Koh, D. M. [4 ]
Collins, D. J. [1 ,2 ,3 ]
Chua, S. [5 ]
Leach, M. O. [1 ,2 ,3 ]
机构：
[1] CR UK, Surrey, England
[2] Inst Canc Res, EPSRC Canc Imaging Ctr, Surrey, England
[3] Royal Marsden Hosp, Surrey, England
[4] Royal Marsden Hosp NHS Fdn Trust, Dept Radiol, Surrey, England
[5] Royal Marsden Hosp NHS Fdn Trust, Dept Nucl Med & PET, Surrey, England
来源：
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2013年 / 702卷
基金：
美国国家卫生研究院; 英国工程与自然科学研究理事会;
关键词：
Diffusion-weighted MRI; PET/CT; PET/MRI; Cancer biomarkers; Lymphoma; SUV; UPTAKE VALUES; ONCOLOGY;
D O I：
10.1016/j.nima.2012.08.083
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
In this technological report, we investigate the utility of whole-body diffusion-weighted MRI (WBDWI) as a prior for defining regions of interest (ROI) in PET data. Due to its comparatively high resolution and excellent lesion-to-background ratio, semi-automatic segmentation is possible in WBDWI. Following rigid registration of PET to WBDWI, a simple, fast and automatic algorithm can be used to define ROIs in PET data. This approach is applied to a test cohort of patients diagnosed with lymphoma who underwent both (18)FDG-PET/CT and WBDWI studies to demonstrate its potential application. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：148 / 151
页数：4
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