Objective: To share an independent pharmacy's experience creating a practical manual for disaster preparedness that incorporates applicable pharmacy regulations, provides a plan to prepare a community pharmacy for disasters, and addresses the pharmacy's duty to the community during disasters. Data sources: A literature search was performed to determine if such a manual or a guide had been published previously. The search returned examples of expectations of hospitals during disasters, but few results were specific to community pharmacy. An Internet search for pharmacy contingency planning returned only a few checklists and descriptive reports of pharmacist involvement in past disasters. Data extraction and synthesis: Public resources available from the Centers for Disease Control and Prevention, Environmental Protection Agency, Drug Enforcement Administration, Department of Public Health, Federal Emergency Management Agency, National Community Pharmacists Association, and American Pharmacists Association were explored. The Iowa State Board of Pharmacy also was contacted. Information was compiled to create a useful guide that addressed disaster planning, risk assessment, and public need during a disaster and that prioritized the needs of the pharmacy and community. Conclusion: Every community pharmacy should have a detailed disaster preparedness manual that is readily accessible and easy to follow. The manual created for Valley Drug focused on continuing pharmacy operations while minimizing disruptions in patient care during a disaster. Our manual included only necessary information required to prepare for, operate during, or recover from a disaster.