Introduction of click chemistry to carotenoids

被引：3

作者：

Hada, Magdolna ^{[1
]}

Nagy, Veronika ^{[1
]}

Takatsy, Aniko ^{[1
]}

Deli, Jozsef ^{[1
]}

Hait, Jan ^{[1
]}

Agocs, Attila ^{[1
]}

机构：

[1] Univ Pecs, Sch Med, Dept Biochem & Med Chem, H-7624 Pecs, Hungary

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 19期

基金：

新加坡国家研究基金会;

关键词：

Carotenoid; Azide-alkyne click reaction; Ester; PEG conjugates; ALKYNES; AZIDES;

D O I：

10.1016/j.tetlet.2012.03.027

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We describe the synthesis of carotenoid derivatives via the azide-alkyne click reaction and optimize the conditions for these sensitive molecules. After finding the mildest conditions possible for the reaction we were able to use the click reaction for the synthesis of PEG-carotenoid conjugates starting from carotenoid pentynoates and PEG azides. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：2480 / 2482

页数：3

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