We present a clinical study based on cross-sectional observation. The study was performed at the Municipal Clinical Hospital No. 1, 2014-2015 in the Obstetric sections no.1, no. 2 and no. 3, and Septic gynaecology section. The study includes 530 women who gave birth by caesarean section. In order to study the degree of implementation of the institutionalized standardized clinical protocol "Antibiotic prophylaxis in caesarean section", we divided the study into two periods: January-March (236 cases - 44.5%+/- 2.16, MI: 40.3%-48.9%) and September to November (294 cases - 55.5%+/- 2.16, CI: 51.1%-59.7%). We drew attention to spesific data: caesarean sectional indications, emergency/planar caesarean operation, time of delivery, alchidic period, number of vaginal exams, complications during surgery, administration of antibiotic, time of administration and the number of doses. At the end of the first year of implementation of the standardized clinical protocol, we noticed a decrease in septic complications.