Temporary portocaval shunt in orthotopic liver transplantation: Need for a standardized approach?

被引:15
|
作者
Davila, Diego [1 ]
Bartlett, Adam [1 ]
Heaton, Nigel [1 ]
机构
[1] Kings Coll Hosp London, Inst Liver Studies, Univ London Kings Coll, Sch Med, London SE5 9RS, England
基金
英国医学研究理事会;
关键词
D O I
10.1002/lt.21603
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Maintenance of portal and systemic venous return during the anhepatic phase of liver transplantation (LT) improves hemodynamic stability. With the piggyback technique, caval return is maintained; however, temporary clamping of the portal vein is still necessary. The use of a temporary portocaval shunt (TPCS) has been proposed to minimize the effect of portal venous interruption. The aim of this study was to perform a systematic review of the literature to determine whether there is evidence to support the routine use of a TPCS in LT. An electronic search of the literature from 1963 to 2007 was performed. A total of 4386 articles were identified, of which 8 met all the criteria and were included in the study. Because of the variability in reporting and the small number of studies, statistical comparison was not possible; however, a trend toward a shorter operative time, less blood product transfusion, and maintenance of higher mean arterial pressures during portal vein clamping was seen in patients with a TPCS. In conclusion, the available evidence, albeit scarce, supports the use of a TPCS in patients undergoing LT. A prospective randomized study of patients most likely to benefit from a TPCS is necessary to substantiate these findings.
引用
收藏
页码:1414 / 1419
页数:6
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