Virus entry: Open sesame

被引：900

作者：

Marsh, M

Helenius, A

机构：

[1] UCL, Cell Biol Unit, MRC, Mol Cell Biol Lab, London WC1E 6BT, England

[2] UCL, Cell Biol Unit, MRC, Dept Biochem & Mol Biol, London WC1E 6BT, England

[3] ETH Honggerberg, Inst Biochem, CH-8093 Zurich, Switzerland

来源：

CELL | 2006年 / 124卷 / 04期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/j.cell.2006.02.007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Detailed information about the replication cycle of viruses and their interactions with host organisms is required to develop strategies to stop them. Cell biology studies, live-cell imaging, and systems biology have started to illuminate the multiple and subtly different pathways that animal viruses use to enter host cells. These insights are revolutionizing our understanding of endocytosis and the movement of vesicles within cells. In addition, such insights reveal new targets for attacking viruses before they can usurp the host-cell machinery for replication.

引用

页码：729 / 740

页数：12

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