Revision of Roux-en-Y Gastric Bypass with Limb Distalization for Inadequate Weight Loss or Weight Regain

Background Of patients undergoing Roux-en-Y gastric bypass (RYGB), 15-35% of patients fail to achieve "adequate" weight loss or regain significant weight. Multiple solutions have been proposed, but not well studied. We report our experience with limb distalization with lengthening the biliopancreatic (BP) limb and shortening the common channel (CC). Methods We retrospectively reviewed data from patients undergoing laparoscopic limb distalization for excess weight loss (EWL) <50% or BMI >35 kg/m(2) after RYGB from 2012 to 2017. The BP limb was lengthened and CC was shortened to 100-200 cm. Perioperative outcomes such as morbidity, weight loss, nutritional deficiencies, comorbidity remission, and operative details were analyzed. Results Twenty-two patients were included. The mean BMI prior to RYGB was 54 +/- 18.5 kg/m(2) and 43.0 +/- 5.5 kg/m(2) prior to limb distalization. The mean follow-up was 18.3 +/- 12.9 months with a mean BMI change, %EWL, and %TWL (total weight loss) of 11.8 +/- 7.4 kg/m(2), 62.3 +/- 32.4%, and 25.4 +/- 14.4%, respectively. The total mean BMI change, %EWL, and %TWL from RYGB was 22.2 +/- 9.9 kg/m(2), 77.8 +/- 23.6%, and 40.2 +/- 13.3%, respectively. Of patients with persistent comorbidities, remission rates of diabetes, hypertension, and gastroesophageal reflux disease were 100%, 17%, and 38%, respectively. The mean operative time was 132.6 +/- 54.4 min and mean hospital stay was 2.2 +/- 1.3 days. Overall morbidity was 27.3%. Three patients (13.6%) developed nutritional deficiencies requiring reversal surgery. Conclusion In patients with inadequate weight loss or weight regain after RYGB, limb distalization with lengthening of the BP limb is an effective procedure for additional weight loss and further improvement of comorbidities. Nutritional complications are a risk, but can be minimized with close follow-up and patient compliance.