Increased ammonium in culture medium reduces the development of human embryos to the blastocyst stage

被引：48
|
作者：
Virant-Klun, I
Tomazevic, T
Vrtacnik-Bokal, E
Vogler, A
Krsnik, M
Meden-Vrtovec, H
机构：
[1] Univ Ljubljana, Med Ctr, Dept Obstet & Gynecol, Reprod Unit, SI-1000 Ljubljana, Slovenia
[2] Univ Ljubljana, Med Ctr, Inst Clin Chem & Biochem, SI-1000 Ljubljana, Slovenia
来源：
FERTILITY AND STERILITY | 2006年 / 85卷 / 02期
关键词：
D O I：
10.1016/j.fertnstert.2005.10.018
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The objective of this prospective study was to evaluate the effect of ammonium accumulated in sequential media and determined by enzymatic spectrophotometric method on the blastocyst development in 281 human embryos from 100 stimulated and natural in vitro fertilization (IVF) cycles. Ammonium concentration was increased in 62% of cycles and was correlated negatively with the blastocyst development after classical IVF, but not after intracytoplasmic sperm injection (ICSI).
引用
收藏
页码：526 / 528
页数：3
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