IgG4 Subclass of Anti-FVIII Antibodies is Correlated to High-Titer Inhibitor, whereas IgG1 Subclass is Related to Low-Titer Inhibitor in Hemophilia A Patients

被引:0
|
作者
Montalvao, S. [1 ]
Trento, T. [1 ]
Veiga, M. [2 ]
Montenegro, M. [2 ]
Streva, A. [3 ]
De Paula, E. [1 ]
Colella, M. [1 ]
Ozelo, M. [1 ]
机构
[1] Univ Estadual Campinas, Hemophilia Unit Claudio LP CorINCT Sangue Hemoctr, Campinas, Brazil
[2] HEMEPAR, Hemoctr Parana, Curitiba, Parana, Brazil
[3] HEMOBA, Hemoctr Bahia, Salvador, BA, Brazil
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:92 / 93
页数:2
相关论文
共 8 条
  • [1] A longitudinal evaluation of anti-FVIII antibodies demonstrated IgG4 subclass is mainly correlated with high-titre inhibitor in haemophilia A patients
    Montalvao, S. A. L.
    Tucunduva, A. C.
    Siqueira, L. H.
    Sambo, A. L. A.
    Medina, S. S.
    Ozelo, M. C.
    HAEMOPHILIA, 2015, 21 (05) : 686 - 692
  • [2] Stability of Monoclonal Antibodies at High-Concentration: Head-to-Head Comparison of the IgG1 and IgG4 Subclass
    Neergaard, Martin S.
    Nielsen, Anders D.
    Parshad, Henrik
    Van de Weert, Marco
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2014, 103 (01) : 115 - 127
  • [3] IMBALANCED SERUM IGG SUBCLASS PATTERN IN TOXIC SHOCK SYNDROME PATIENTS - DEFICIENCY OF SPECIFIC IGG1 AND IGG4 SUBCLASS ANTIBODIES TO TOXIC SHOCK SYNDROME TOXIN-1
    CHRISTENSSON, B
    JOHANSSON, PJH
    OXELIUS, VA
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 1986, 66 (02): : 443 - 449
  • [4] Levels of Anti-FVIII IgG4 and Total IgG Are Biomarkers of Immune Tolerance Induction Failure in Patients with Inherited Hemophilia a and High-Responding Inhibitors
    Rezende, Suely Meireles
    Ayala, Brendon
    Camelo, Ricardo
    Dias, Maise M.
    Oliveira, Andrea G.
    Franco, Vivian K. B.
    Cerqueira, Monica H.
    Lorenzato, Claudia S.
    Ribeiro, Rosangela A.
    Callado, Fabia M. R. A.
    Cerqueira, Maria Aline
    Etto, Leina Y.
    Roberti, Maria do Rosario
    Anegawa, Tania H.
    Pinto, Ieda
    Chaves, Daniel Goncalves
    BLOOD, 2023, 142
  • [5] Rapid Acquisition of Immunologic Tolerance to Factor VIII and Disappearance of Anti-factor VIII IgG4 After Prophylactic Therapy in a Hemophilia A Patient With High-titer Factor VIII Inhibitor
    Moorehead, Paul C.
    Thibeault, Lisa
    Tuttle, Angie
    Grabell, Julie
    Dwyre, Louise
    Silva, Mariana
    James, Paula
    Lillicrap, David
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2015, 37 (04) : E220 - E222
  • [6] SUBCLASS DISTRIBUTION OF HUMAN ANTI-STAPHYLOCOCCUS-AUREUS ALPHA-TOXIN ANTIBODIES - SUGGESTION OF AN IGG1, IGA1, IGG4 SWITCH PATTERN
    HAMMARSTROM, L
    PERSSON, MAA
    SMITH, CIE
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1984, 20 (03) : 247 - 250
  • [7] Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass - Prediction of viscosity through protein-protein interaction measurements
    Neergaard, Martin S.
    Kalonia, Devendra S.
    Parshad, Henrik
    Nielsen, Anders D.
    Moller, Eva H.
    van de Weert, Marco
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2013, 49 (03) : 400 - 410
  • [8] COVID-19 patients often show high-titer non-platelet-activating anti-PF4/heparin IgG antibodies
    Brodard, Justine
    Kremer Hovinga, Johanna A.
    Fontana, Pierre
    Studt, Jan-Dirk
    Gruel, Yves
    Greinacher, Andreas
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2021, 19 (05) : 1294 - 1298