Investigation of the Assembly Behavior of an Amphiphilic Lipopeptide at the Liquid Crystal-Aqueous Interface

被引：19

作者：

Yang, Xiuxiu ^{[1
]}

Tan, Yi ^{[1
]}

Li, Fangyi ^{[2
]}

Yu, Qing ^{[2
]}

Tan, Suk Fun ^{[1
]}

Chen, Yongxiang ^{[2
]}

Yang, Zhongqiang ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China

[2] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing 100084, Peoples R China

来源：

LANGMUIR | 2019年 / 35卷 / 07期

基金：

中国国家自然科学基金;

关键词：

ORDERING TRANSITIONS; DNA; BINDING; REORIENTATION; PRINCIPLES; MOLECULES; DROPLETS;

D O I：

10.1021/acs.langmuir.8b03294

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this article, we designed an amphiphilic lipopeptide molecule, 5(6)-carboxyfluorescein-KKKKKKSKTK-Cys(C12H25)-OMe (FAM-lipopeptide-C12), and studied its assembly behavior at the 4-cyano-4'-pentylbiphenyl (5CB)-aqueous interface. The ordering transitions of liquid crystals (LCs) revealed that FAM-lipopeptide-C12 can assemble at the LC-aqueous interface (both planar and curved interfaces). The assembly can be destroyed by adding trypsin, which catalyzes the hydrolysis of lipopeptides. Fluorescence measurements further confirmed the assembly and deassembly behavior of FAM-lipopeptide-C12 at the LC-aqueous interface. Overall, our work provides a general method for the construction of a biointerface by directly assembling amphiphilic lipopeptides at the LC-aqueous interface, which can potentially be used in selectively detecting the activity of specific enzymes and other biomolecular interactions.

引用

页码：2490 / 2497

页数：8

共 50 条

[1] The Assembly of DNA Amphiphiles at Liquid Crystal-Aqueous Interface
Zhou, Jingsheng
Dong, Yuanchen
Zhang, Yiyang
Liu, Dongsheng
Yang, Zhongqiang
NANOMATERIALS, 2016, 6 (12):
[2] Surfactant-DNA interactions at the liquid crystal-aqueous interface
McUmber, Aaron C.
Noonan, Patrick S.
Schwartz, Daniel K.
SOFT MATTER, 2012, 8 (16) : 4335 - 4342
[3] Orientational Transitions of Liquid Crystal Driven by Hydrogen-Bond Interaction at the Liquid Crystal-Aqueous Interface
Liao Zhi-Jian
Qin Zhen-Li
Du Si-Nan
Li Si-Yu
Chen Guan-Hou
Zuo Fang
Luo Jian-Bin
ACTA PHYSICO-CHIMICA SINICA, 2015, 31 (09) : 1733 - 1740
[4] Design of liquid crystal-aqueous interface for detection of calcium ions using protein as recognition probe
Devi, Manisha
Sil, Soma
Pani, Ipsita
Gupta, Tarang
Pal, Santanu Kumar
LIQUID CRYSTALS, 2024, 51 (01) : 1 - 9
[5] Construction of aptamer-based liquid crystal-aqueous sensing interface for the sensitive detection of dopamine
Huang, Runqing
Xia, Linle
Jiang, Li
Shui, Qianqian
Deng, Jinan
Yang, Jun
LIQUID CRYSTALS, 2024, 51 (10) : 1690 - 1698
[6] Principles for Manipulation of the Lateral Organization of Aqueous-Soluble Surface-Active Molecules at the Liquid Crystal-Aqueous Interface
Gupta, Jugal K.
Abbott, Nicholas L.
LANGMUIR, 2009, 25 (04) : 2026 - 2033
[7] Elucidating liquid crystal-aqueous interface for the study of cholesterol-mediated action of a β-barrel pore forming toxin
Gupta, Tarang
Mondal, Anish Kumar
Pani, Ipsita
Chattopadhyay, Kausik
Pal, Santanu Kumar
SOFT MATTER, 2022, 18 (28) : 5293 - 5301
[8] Self-assembly of lipids and proteins at the aqueous-liquid crystal interface
Meli, Maria-Victoria
Brake, Jeffrey M.
Gupta, Jugal K.
Teren, Sarah
Abbott, Nicholas L.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 233
[9] X-ray reflectivity reveals ionic structure at liquid crystal-aqueous interfaces
Hallett, James E.
Hayward, Dominic W.
Arnold, Thomas
Bartlett, Paul
Richardson, Robert M.
SOFT MATTER, 2017, 13 (33) : 5535 - 5542
[10] Highly selective aptasensor for optical detection of whole cell gastrointestinal pathogen Shigella dysenteriae at label-free liquid crystal-aqueous interface
Das, Sayani
Chakraborty, Ranadhir
Kula, Przemyslaw
Mclaughlin, James
Roy, Susanta Sinha
APPLIED PHYSICS LETTERS, 2025, 126 (02)

← 1 2 3 4 5 →