Validation and IMRT/VMAT delivery quality of a preconfigured fast-rotating O-ring linac system

被引:45
|
作者
De Roover, Robin [1 ]
Crijns, Wouter [1 ,2 ]
Poels, Kenneth [2 ]
Michiels, Steven [1 ]
Nulens, An [2 ]
Vanstraelen, Bianca [2 ]
Petillion, Saskia [2 ]
De Brabandere, Marisol [2 ]
Haustermans, Karin [1 ,2 ]
Depuydt, Tom [1 ,2 ]
机构
[1] KU Leuven Univ Leuven, Dept Oncol, Lab Expt Radiotherapy, Herestr 49, B-3000 Leuven, Belgium
[2] Univ Hosp Leuven, Dept Radiat Oncol, Herestr 49, B-3000 Leuven, Belgium
关键词
IMRT/VMAT; preconfigured system; validation; MODULATED RADIATION-THERAPY; PLANNING DOSE CALCULATIONS; QUANTITATIVE-EVALUATION; MEGAVOLTAGE PHOTON; CLINICAL-USE; DOSIMETRY; IMRT; QA; IMPLEMENTATION; RADIOTHERAPY;
D O I
10.1002/mp.13282
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose A fast-rotating O-ring dedicated intensity modulated radiotherapy (IMRT)/volumetric modulated arc therapy (VMAT) delivery system, the Halcyon, is delivered by default with a fully preconfigured photon beam model in the treatment planning system (TPS). This work reports on the validation and achieved IMRT/VMAT delivery quality on the system. Methods Acceptance testing followed the vendor's installation product acceptance and was supplemented with mechanical QA. The dosimetric calibration was performed according to the IAEA TRS-398 code-of-practice, delivering 600 cGy/min at 10 cm depth, a 90 cm source-surface distance, and a 10 x 10 cm(2) field size. The output factors, multileaf collimator (MLC) transmission and dosimetric leaf gap (DLG) were validated by comparing measurements with the modeled values in the TPS. Validation of IMRT/VMAT was conducted following AAPM reports (MPPG 5.a, TG-119). Next, dose measurements were performed for end-to-end (E2E) checks in heterogeneous anthropomorphic phantoms using radiochromic film in multiple planes and using ionization chambers (IC) point measurements. E2E checks were performed for VMAT (cranial, rectum, spine, and head and neck) and IMRT (lung). Additionally, IROC Houston mailed dosimetry audits were performed for the beam calibration and E2E measurements using a thorax phantom (IMRT) and a head and neck phantom (VMAT). Lastly, extensive patient-specific QA was performed for the first patients of each new indication, 26 in total (n(rectum) = 2, n(spine) = 5, n(lung) = 5, n(esophagus) = 2, n(head and neck) = 7, n(cranial) = 5), treated on the fast-rotating O-ring linac. The patient-specific QA followed the AAPM TG-218 guidelines and comprised of portal dosimetry, ArcCHECK diode array, radiochromic film dosimetry in a MultiCube phantom, and IC point measurements. Results The measured output factors showed an agreement <1% for fields >= 3 x 3 cm(2). Field sizes <= 2 x 2 cm(2) had a difference of <2%. The measured single-layer MLC transmission was 0.42 +/- 0.01% and the measured DLG was 0.27 +/- 0.22 mm. The AAPM MPPG 5.a measurements were fully compliant with the guideline criteria. Dose differences larger than 2% were found for the PDD at large depths (>25 cm). TG-119's confidence limits were achieved for the VMAT point dose measurements and for both the IMRT and VMAT radiochromic film measurements. The TG-119 confidence limits were not achieved for IMRT point dose measurements in both the target (5.9%) and the avoidance structure (6.4%). All E2E tests had point differences below 2.3% and gamma agreement scores above 90.6%. The IROC beam calibration audit showed agreement of Conclusions The fast-rotating O-ring linac and its preconfigured TPS are compliant with the international commissioning criteria of AAPM MPPG 5.a and AAPM TG-119. E2E measurements on heterogeneous anthropomorphic phantoms were within clinically acceptable tolerances. IROC Houston's audits satisfied the credentialing criteria. This work comprises the first extensive dataset reporting on the preconfigured fast-rotating O-ring linac.
引用
收藏
页码:328 / 339
页数:12
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