Photoprotective activity of medicinal plants from the caatinga used as anti-inflammatories

被引:9
|
作者
Andrade, Bruno de Almeida [1 ]
Chernichiarro Correa, Allan Jonathan [1 ]
Soares Gomes, Ana Klarissa [1 ]
da Silva Neri, Patricia Maria [1 ]
da Silva Peixoto Sobrinho, Tadeu Jose [2 ]
de Sousa Araujo, Thiago Antonio [1 ,3 ]
Nobre de Almeida e Castro, Valerium Thijan [3 ]
Cavalcanti de Amorim, Elba Lucia [1 ]
机构
[1] Univ Fed Pernambuco, Dept Pharmaceut Sci, St Arthur Sa, Recife, PE, Brazil
[2] Univ Ctr Valley Ipojuca, Nurse Coordinat, Caruaru, Brazil
[3] Univ Ctr Mauricio de Nassau, Dept Hlth, Recife, PE, Brazil
关键词
Antioxidant activity; Caatinga; flavonoids; phytochemistry; sun protection factor; SUN PROTECTION FACTOR; IN-VITRO ANTIOXIDANT; EXTRACTS; CYTOTOXICITY; SUNSCREENS; SELECTION; CAPACITY; TANNINS; L;
D O I
10.4103/pm.pm_482_18
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Background: Exposure to ultraviolet (UV) radiation may cause photoaging, unsightly marks, or dangerous lesions, such as carcinomas and/or melanomas. Sun filters are substances capable of absorbing, reflecting, or refracting UV radiation and thus protect the skin from direct exposure to sunlight. The current trend in the cosmetics industry, in Brazil, is to rationally explore local biodiversity as a way of developing products of natural origin, especially derived from plants. Objective: The present study aims to determine the in vitro sun protection factor (SPF) of 15 species from the Caatinga region used in popular medicine as anti-inflammatories. Materials and Methods: Samples of duly identified plant species were dried and ground and hydroethanolic extracts were obtained (80:20). Spectrophotometric analyses were carried out to determine the SPF, antioxidant activity, and quantification of secondary metabolites. In vitro calculation of SPF was based on the method developed by Mansur. Results: Erythrina velutina Willd. had the best SPF of 9.71 1.29 at a concentration of 100 mg/L. Conclusion: The study showed that native species to the Caatinga used by the local population to treat inflammatory disorders have good photoprotective potential and could be used for pharmaceutical preparations to this end.
引用
收藏
页码:356 / 361
页数:6
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