Longer Distance From Dialysis Facility to Transplant Center Is Associated With Lower Access to Kidney Transplantation

被引:5
|
作者
Whelan, Adrian M. [1 ]
Johansen, Kirsten L. [1 ,2 ]
McCulloch, Charles E. [3 ]
Adelmann, Dieter [4 ]
Niemann, Claus U. [4 ,5 ]
Roll, Garrett R. [5 ]
Siyahian, Salpi [1 ]
Grimes, Barbara [3 ]
Ku, Elaine [1 ,3 ,6 ]
机构
[1] Univ Calif San Francisco, Dept Med, Div Nephrol, 533 Parnassus Ave,U404,Box 0532, San Francisco, CA 94143 USA
[2] Hennepin Cty Med Ctr, Dept Med, Div Nephrol, Minneapolis, MN 55415 USA
[3] Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA USA
[4] Univ Calif San Francisco, Dept Anesthesia & Crit Care, San Francisco, CA 94143 USA
[5] Univ Calif San Francisco, Dept Surg, Div Transplant Surg, San Francisco, CA USA
[6] Univ Calif San Francisco, Dept Pediat, Div Pediat Nephrol, San Francisco, CA USA
来源
TRANSPLANTATION DIRECT | 2020年 / 6卷 / 10期
基金
美国国家卫生研究院;
关键词
SURVIVAL; DISPARITIES; OWNERSHIP; FAILURE; OBESITY;
D O I
10.1097/TXD.0000000000001048
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Background. Rates of kidney transplantation vary substantially across dialysis facilities in the United States. Whether distance between the dialysis facility and transplant center associates with variations in transplantation rates has not been examined. Methods. We performed a retrospective study of adults treated with dialysis between 2005 and 2015, according to the US Renal Data System. We examined the association between distance from dialysis facility to transplant center and time to kidney transplantation (primary outcome) and waitlist registration (secondary outcome) using Fine-Gray models. We also performed sensitivity analyses using the distance from each patient's dialysis facility to the nearest transplant center as the predictor so that patients who were never registered on the waitlist (and therefore would not have a transplant center) could be included. Results. In total, 178 885 waitlisted patients were included for our primary analysis. As distance between dialysis facility and transplant center increased, lower hazard of transplantation (subhazard ratio [HR], 0.92; 95% confidence interval [CI], 0.91-0.94, if distance was 10 to <50 miles; sub-HR, 0.90; 95% CI, 0.88-0.92, if distance >= 50 miles compared with <10 miles) was noted. We also found a weak association between longer distance and hazard of waitlist registration (sub-HR, 0.96; 95% CI, 0.94-0.97, if distance was >= 50 miles versus <10 miles). Findings were similar in sensitivity analyses using distance between dialysis facility and the nearest transplant center (N = 1 149 721). Conclusions. Patients receiving dialysis in facilities located further away from transplant centers have lower hazard of kidney transplantation. Developing strategies to address barriers to transplantation in patients receiving dialysis at facilities located far away from a transplant center may help improve disparities in transplantation rates.
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页数:8
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