Candida auris Infection and Biofilm Formation: Going Beyond the Surface

Purpose of Review Emergent fungal pathogenC. aurisis spreading in hospitals throughout the world and mortality rates for patients with invasive disease approach 60%. This species exhibits a heightened capacity to colonize skin, persist on hospital surfaces, rapidly disseminate in healthcare settings, and resist antifungal therapy. Recent Findings Current investigations show thatC. aurisproduces biofilms, surface-adherent communities that resist antifungals and withstand desiccation. These biofilms form whenC. aurisis growing on skin or in conditions expected in the hospital environment and on implanted medical devices. Here, we will highlight the topic of biofilm formation byC. auris. We illustrate how this process influences resistance to antimicrobials and promotes nosocomial transmission.