Acquisition of carbapenem resistance in multiresistant Klebsiella pneumoniae isolates of sequence type 11 at a university hospital in China

被引:21
|
作者
Liu, Yang [1 ]
Li, Xiang-Yang [2 ]
Wan, La-Gen [1 ]
Jiang, Wei-Yan [2 ]
Yang, Jing-Hong [2 ]
Li, Fang-Qu [2 ]
机构
[1] Nanchang Univ, Affiliated Hosp 1, Dept Bacteriol, Nanchang 330006, Peoples R China
[2] Wenzhou Med Coll, Affiliated Hosp 2, Dept Clin Microbiol, Wenzhou 325027, Peoples R China
关键词
Carbapenem resistance; Klebsiella; 16S rRNA methyltransferase; Multilocus sequence typing; MOLECULAR CHARACTERIZATION; GENES;
D O I
10.1016/j.diagmicrobio.2013.02.002
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Four closely related KPC-producing Klebsiella pneumoniae strains, which were isolated from the patients with neonatal sepsis, harbored bla(CTX-M-14), bla(TEM-1), bla(CTX-M-15), bla(SHV-11), bla(SHV-12), class 1 integron, qnrS1, acc(6')-lb-cr, and rmtB genes. Multilocus sequence typing experiments showed that all isolates but Kp122 were proven to share the same sequence type (ST), ST11. These isolates have not yet been previously reported in a university-affiliated children's hospital or in the city of Wenzhou. (C) 2013 Published by Elsevier Inc.
引用
收藏
页码:241 / 243
页数:3
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