Estrogen replacement therapy for the potential treatment or prevention of Alzheimer's disease

被引：0
|
作者：
Miller, MM [1 ]
Monjan, AA [1 ]
Buchholtz, NS [1 ]
机构：
[1] NIA, Neurosci & Neuropsychol Aging Program, NIH, Bethesda, MD 20892 USA
来源：
SELECTIVE ESTROGEN RECEPTOR MODULATORS (SERMS) | 2001年 / 949卷
关键词：
Alzheimer's disease; estrogen; cognitive function; clinical trials; epidemiology; memory;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Alzheimer's disease (AD) is an irreversible, progressive brain disorder that occurs gradually and results in memory loss, behavior and personality changes, and a decline in cognitive abilities. Although basic biological data suggest that estrogen may have neuroprotective and neuroenhancing functions, a number of studies have produced conflicting findings on the use of estrogen for maintaining cognitive function in older people. This review summarizes clinical studies that have examined the effects of estrogen in women with AD.
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收藏
页码：223 / 234
页数：12
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