Role of dopamine receptors in the kidney in the regulation of blood pressure

被引：80
|
作者：
Jose, PA
Eisner, GM
Felder, RA
机构：
[1] Georgetown Univ, Med Ctr, Dept Pediat, Phys Healthcare Ctr, Washington, DC 20007 USA
[2] Georgetown Univ, Med Ctr, Dept Physiol & Biophys, Washington, DC 20007 USA
[3] Georgetown Univ, Med Ctr, Dept Med, Washington, DC 20007 USA
[4] Univ Virginia, Hlth Sci Ctr, Dept Pathol, Charlottesville, VA USA
来源：
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION | 2002年 / 11卷 / 01期
关键词：
D O I：
10.1097/00041552-200201000-00013
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Regulation by dopamine of cardiovascular function, renal function and systemic blood pressure regulation is multifaceted. Each of the five dopamine receptor subtypes participates in the regulation of blood pressure by mechanisms specific for the subtype. Some receptors regulate blood pressure by influencing the central or peripheral nervous system; others influence epithelial transport and regulate the secretion and receptors of several humoral agents. The D-1, D-3, and D-4 receptors interact with the renin-angiotensin system, while the D-2 and D-5 receptors interact with the sympathetic nervous system to regulate blood pressure. Curr Opin Nephrol Hypertens 11:87-92. (C) 2002 Lippincott Williams & Wilkins.
引用
收藏
页码：87 / 92
页数：6
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