Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer

被引：1

作者：

Ma, Guiying ^{[1
,2
,3
]}

Zhang, A. Ping ^{[1
,2
,3
]}

Yan, Guofeng ^{[1
,2
,3
]}

Bai, Yinbing ^{[1
,2
,3
]}

Hu, Yichuan ^{[4
,5
]}

Ye, Xuesong ^{[4
]}

机构：

[1] Zhejiang Univ, Ctr Opt & Electromagnet Res, State Key Lab Modern Opt Instrumentat, Hangzhou 310058, Zhejiang, Peoples R China

[2] Zhejiang Normal Univ, Zhejiang Prov Key Lab Sensing Technol, Joint Res Lab Optic, Hangzhou, Peoples R China

[3] Zhejiang Univ, Hangzhou, Peoples R China

[4] Zhejiang Univ, Minist Educ Key Lab Biomed Engn Hangzhou, Coll Biomed Engn & Instrument Sci, Biosensor Natl Special Lab, Hangzhou, Zhejiang, Peoples R China

[5] Zhejiang Univ Technol, Zhijiang Coll, Hangzhou, Zhejiang, Peoples R China

来源：

22ND INTERNATIONAL CONFERENCE ON OPTICAL FIBER SENSORS, PTS 1-3 | 2012年 / 8421卷

关键词：

label-free biosensor; DNA sensor; optical fiber interferometer; SENSOR;

D O I：

10.1117/12.974989

中图分类号：

TP7 [遥感技术];

学科分类号：

081102 ; 0816 ; 081602 ; 083002 ; 1404 ;

摘要：

The fabrication and characterization of a highly sensitive DNA biosensor based on thin-core fiber modal interferometer (TCFMI) are presented. The TCFMI is made by using a thin-core fiber (TCF) with core diameter of similar to 3.0 mu m and etched by using Hydrofluoric (HF) acid solution for sensitivity enhancement. A thin layer of polymer (PLL, poly-L-lysine) was coated on the sensor surface and experimentally demonstrated for the detection of hybridization of deoxyribonucleic acid (DNA).

引用

页数：4

共 50 条

[1] Label-free fiber optic biosensor based on thin-core modal interferometer
Yu, Wenjie
Lang, Tingting
Bian, Jicheng
Kong, Wen
[J]. SENSORS AND ACTUATORS B-CHEMICAL, 2016, 228 : 322 - 329
[2] Investigation of a cladding-etched thin-core fiber modal interferometer and its application for refractive index sensing
Yan, Guofeng
Zhang, A. Ping
Ma, Guiying
He, Sailing
[J]. 2012 ASIA COMMUNICATIONS AND PHOTONICS CONFERENCE (ACP), 2012,
[3] A high-sensitivity refractometer based on etched thin-core fiber modal interferometer
Jiang, Meng
Wang, Ze-Ming
Zhao, Zhong-Ze
Li, Kun
Zhang, Yixin
[J]. MICROWAVE AND OPTICAL TECHNOLOGY LETTERS, 2017, 59 (01) : 53 - 56
[4] Label-Free Detection of DNA Hybridization Utilizing Dual S-Tapered Thin-Core Fiber Interferometer
Zhang, Xu
Liu, Bo
Zhang, Hao
Song, Binbin
Wu, Jixuan
Duan, Shaoxiang
[J]. JOURNAL OF LIGHTWAVE TECHNOLOGY, 2019, 37 (11) : 2762 - 2767
[5] Refractive index and temperature-sensing characteristics of a cladding-etched thin core fiber interferometer
Wang, Weiying
Dong, Xinran
Chu, Dongkai
Hu, Youwang
Sun, Xiaoyan
Duan, Ji-An
[J]. AIP ADVANCES, 2018, 8 (05)
[6] Fiber-optic accelerometer based on a modal interferometer using a thin-core fiber
Wang, Xue
Wu, Xuqiang
Li, Shili
Ge, Qiang
He, Tianbo
Yu, Benli
[J]. OPTICA APPLICATA, 2015, 45 (03) : 317 - 325
[7] Simultaneous measurement of displacement and temperature based on thin-core fiber modal interferometer
Wu, Jixuan
Miao, Yinping
Song, Binbin
Lin, Wei
Zhang, Kailiang
Zhang, Hao
Liu, Bo
Yao, Jianquan
[J]. OPTICS COMMUNICATIONS, 2015, 340 : 136 - 140
[8] Highly Sensitive Refractive Index Sensor Based on a Cladding-Etched Thin-Core Fiber Sandwiched between Two Single-Mode Fibers
Xu Ben
Li Yi
Dong Xin-Yong
Jin Shang-Zhong
Zhang Zai-Xuan
[J]. CHINESE PHYSICS LETTERS, 2012, 29 (09)
[9] Fiber-Optic Catalytic Hydrogen Sensor Based on Thin-core Fiber Modal Interferometer
Liu, Jing
Zhang, Yebin
Zhang, A. Ping
Tian, Hua
An, Quanfu
[J]. 2012 ASIA COMMUNICATIONS AND PHOTONICS CONFERENCE (ACP), 2012,
[10] Composite Modal Interferometer for Simultaneous Triple-Parameter Measurement Based on Cascaded No-Cladding Fiber and Thin-Core Fiber Structure
Zhang, Meng
Hou, Liangtao
Zhang, Hui
Zhang, Xudong
Yang, Jiuru
[J]. IEEE ACCESS, 2020, 8 : 180133 - 180139

← 1 2 3 4 5 →