Click Chemistry Inspired Synthesis of Glycoporphyrin Dendrimers

被引:70
|
作者
Kushwaha, Divya [1 ]
Tiwari, Vinod K. [1 ]
机构
[1] Banaras Hindu Univ, Fac Sci, Dept Chem, Varanasi 221005, Uttar Pradesh, India
来源
JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 78卷 / 16期
关键词
PHOTODYNAMIC THERAPY; BINDING-PROPERTIES; ALPHA-THIOSIALODENDRIMERS; PORPHYRIN CORES; GLYCODENDRIMERS; TRIAZOLE; DERIVATIVES; LECTIN; CELLS; PHOTOCYTOTOXICITY;
D O I
10.1021/jo4012392
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A series of porphyrin-cored glycodendrimers containing 8, 12, 16, and 24 beta-D-glucopyranose units at the periphery, have been synthesized by convergent methodology using click chemistry. The structure of developed dendrimers is established by H-1 and C-13 NMR, IR, MALDI-TOF MS, and SEC analysis. Absorption-emission behavior of dendrimers and its modulation under the influence of the dendritic environment is also investigated.
引用
收藏
页码:8184 / 8190
页数:7
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