Western blot analysis as an aid for the diagnosis of cutaneous leishmaniasis due to Leishmania major

被引：12

作者：

Pomares, Christelle ^{[1
,2
]}

Despierres, Laura ^{[1
]}

del Giudice, Pascal ^{[3
]}

Delaunay, Pascal ^{[1
,2
]}

Michel, Gregory ^{[2
]}

Ferrua, Bernard ^{[2
]}

Marty, Pierre ^{[1
,2
]}

机构：

[1] Univ Nice Sophia Antipolis, Ctr Hosp Univ Nice, Serv Parasitol Mycol, Fac Med, Nice, France

[2] Batiment Univ Archimed, INSERM, U895, F-06204 Nice 3, France

[3] Ctr Hosp, Serv Derrnatol & Infectiol, Frejus, France

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2012年 / 106卷 / 07期

关键词：

Cutaneous leishmaniasis; Leishmania major; Serodiagnosis; Western blot; ANTIGENS; INFANTUM;

D O I：

10.1016/j.trstmh.2012.03.001

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Cutaneous leishmaniasis (CL) due to Leishmania major is endemic in the Old World. To evaluate the diagnostic value of Western blot (WB) compared with IFAT, we tested serum samples from 45 patients with proven CL Twenty-one (47%) patients were positive by IFAT and all patients were positive by WB with specific bands against 14 kDa and/or 18 kDa Leishmania antigens. Our results suggest that WB could be a useful non-invasive tool for the diagnosis of CL caused by L. major. (C) 2012 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

引用

页码：452 / 454

页数：3

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