Expanding indications for pancreatic islet cell transplantation

Purpose of review We aimed to summarize the current state of performing pancreatic islet autotransplantation (IAT) for indications other than total pancreatectomy for chronic pancreatitis. Recent findings The current article will review expanded indications for IAT including partial pancreatectomy for benign inflammatory disease, trauma, pancreatic islet cell tumor and pancreatic adenocarcinoma. In the context of more access for IAT as more centers are offering this clinical service, these expanded indications will continue to push the limits of our ability to make IAT accessible. Pancreatic islet cell transplantation is increasingly being used for new indications related to benign disease and malignancy. We expect continued expansion of its use as IAT becomes more accessible.