PR671, the first proteasome inhibitor that selectively inhibits the bortezomib/carfilzomib insensitive β2 proteasome subunits, overcomes bortezomib/carfilzomib resistance in myeloma cells in vitro

被引:0
|
作者
Driessen, C. [1 ]
Kraus, M. [1 ]
van der Linden, W. A. [2 ]
Bader, J. [1 ]
Overkleeft, H. S. [2 ]
机构
[1] Kantonsspital, St Gallen, Switzerland
[2] Leiden Univ, Inst Chem, Leiden, Netherlands
来源
ONKOLOGIE | 2012年 / 35卷
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:176 / 176
页数:1
相关论文
共 36 条
  • [1] Nelfinavir augments proteasome inhibition by bortezomib in myeloma cells and overcomes bortezomib and carfilzomib resistance
    Kraus, M.
    Bader, J.
    Overkleeft, H.
    Driessen, C.
    [J]. BLOOD CANCER JOURNAL, 2013, 3 : e103 - e103
  • [2] Nelfinavir augments proteasome inhibition by bortezomib in myeloma cells and overcomes bortezomib and carfilzomib resistance
    M Kraus
    J Bader
    H Overkleeft
    C Driessen
    [J]. Blood Cancer Journal, 2013, 3 : e103 - e103
  • [3] The novel β2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells
    Kraus, Marianne
    Bader, Juergen
    Geurink, Paul P.
    Weyburne, Emily S.
    Mirabella, Anne C.
    Silzle, Tobias
    Shabaneh, Tamer B.
    van der Linden, Wouter A.
    de Bruin, Gerjan
    Haile, Sarah R.
    van Rooden, Eva
    Appenzeller, Christina
    Li, Nan
    Kisselev, Alexei F.
    Overkleeft, Herman
    Driessen, Christoph
    [J]. HAEMATOLOGICA, 2015, 100 (10) : 1350 - 1360
  • [4] Proteasome Maturation Protein (pomp) Is Associated With Proteasome Inhibitor Resistance In Myeloma, and Its Suppression Enhances The Activity Of Bortezomib and Carfilzomib
    Li, Bingzong
    Wang, Hua
    Orlowski, Robert Z.
    [J]. BLOOD, 2013, 122 (21)
  • [5] Combination Therapy of Selinexor with Bortezomib or Carfilzomib Overcomes Drug Resistance to Proteasome Inhibitors (PI) in Human Multiple Myeloma
    Sullivan, Daniel M.
    Kashyap, Trinayan
    Dawson, Jana L.
    Landesman, Yosef
    Grant, Steven
    Shain, Kenneth H.
    Dai, Yun
    Kauffman, Michael
    Shacham, Sharon
    Turner, Joel C.
    [J]. BLOOD, 2015, 126 (23)
  • [6] Specific Cell-Permeable Inhibitor of Proteasome Trypsin-like Sites Selectively Sensitizes Myeloma Cells to Bortezomib and Carfilzomib
    Mirabella, Anne C.
    Pletnev, Alexandre A.
    Downey, Sondra L.
    Florea, Bogdan I.
    Shabaneh, Tamer B.
    Britton, Matthew
    Verdoes, Martijn
    Filippov, Dmitri V.
    Overkleeft, Herman S.
    Kisselev, Alexei F.
    [J]. CHEMISTRY & BIOLOGY, 2011, 18 (05): : 608 - 618
  • [7] Combination Therapy with Bortezomib or Carfilzomib and Selinexor Induces Nuclear Localization of Ikba and Overcomes Acquired Proteasome Inhibitor Resistance in Human Multiple Myeloma
    Turner, Joel G.
    Kashyap, Trinayan
    Dawson, Jana L.
    Gomez, Juan A.
    Bauer, Alexis
    Grant, Steven
    Dai, Yun
    Shain, Kenneth H.
    Meads, Mark B.
    Landesman, Yosef
    Sullivan, Daniel M.
    [J]. BLOOD, 2016, 128 (22)
  • [8] Pharmacogenomic Study of Carfilzomib in Relapsed/Refractory Multiple Myeloma Suggests That Carfilzomib Is a More Potent Proteasome Inhibitor Than Bortezomib
    Zhang, Qing
    Heuck, Christoph
    Qiang, Ya-Wei
    van Rhee, Frits
    Waheed, Sarah
    Bailey, Clyde
    Panozzo, Susan B.
    Epstein, Joshua
    Barlogie, Bart
    Usmani, Saad Z.
    [J]. BLOOD, 2012, 120 (21)
  • [9] XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IkBa and overcomes acquired proteasome inhibitor resistance in human multiple myeloma
    Turner, Joel G.
    Kashyap, Trinayan
    Dawson, Jana L.
    Gomez, Juan
    Bauer, Alexis A.
    Grant, Steven
    Dai, Yun
    Shain, Kenneth H.
    Meads, Mark
    Landesman, Yosef
    Sullivan, Daniel M.
    [J]. ONCOTARGET, 2016, 7 (48) : 78896 - 78909
  • [10] The proteasome inhibitor bortezomib inhibits the growth of canine malignant melanoma cells in vitro and in vivo
    Ito, Keita
    Kobayashi, Masato
    Kuroki, Shiori
    Sasaki, Yu
    Iwata, Taisuke
    Mori, Kohei
    Kuroki, Tetsuya
    Ozawa, Yuta
    Tetsuka, Masanori
    Nakagawa, Tomoko
    Hiroi, Teruyo
    Yamamoto, Hitomi
    Ono, Kenichiro
    Washizu, Tsukimi
    Bonkobara, Makoto
    [J]. VETERINARY JOURNAL, 2013, 198 (03): : 577 - 582