Control and manipulation of microfluidic flow via elastic deformations

被引:43
|
作者
Holmes, Douglas P. [1 ]
Tavakol, Behrouz [1 ]
Froehlicher, Guillaume [2 ]
Stone, Howard A. [2 ]
机构
[1] Virginia Tech, Dept Engn Sci & Mech, Blacksburg, VA 24061 USA
[2] Princeton Univ, Dept Mech & Aerosp Engn, Princeton, NJ 08544 USA
关键词
STRAIN GRADIENTS CORRELATE; MECHANICS; SURFACE; SITES;
D O I
10.1039/c3sm51002f
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
We utilize elastic deformations via mechanical actuation to control and direct fluid flow within a flexible microfluidic device. The device consists of a microchannel with a flexible arch prepared by the buckling of a thin elastic film. The deflection of the arch can be predicted and controlled using the classical theory of Euler buckling. The fluid flow rate is then controlled by coupling the elastic deformation of the arch to the gap within the microchannel, and the results compared well with analytical predictions from a perturbation calculation and numerical simulations. We demonstrate that placement of these flexible valves in series enables directed flow towards regions of externally applied mechanical stress. The simplicity of the experimental approach provides a general design for advanced functionality in portable microfluidics, self-healing devices, and in situ diagnostics.
引用
收藏
页码:7049 / 7053
页数:5
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