Late onset bone marrow transplant nephropathy

被引：14

作者：

Oyama, Y ^{[1
]}

Komatsuda, A ^{[1
]}

Imai, H ^{[1
]}

Ohtani, H ^{[1
]}

Hamai, K ^{[1
]}

Wakui, H ^{[1
]}

Miura, AB ^{[1
]}

Nakamoto, Y ^{[1
]}

机构：

[1] AKITA UNIV,SCH MED,DEPT INTERNAL MED 3,AKITA 010,JAPAN

来源：

INTERNAL MEDICINE | 1996年 / 35卷 / 06期

关键词：

complication; chemotherapy; irradiation; cyclosporin A; graft-versus host disease;

D O I：

10.2169/internalmedicine.35.489

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a patient who exhibited proteinuria and renal failure 93 months after receiving an allogeneic bone marrow transplantation (BMT) from his HLA-identical brother. A renal biopsy specimen revealed segmental sclerosis, mesangiolysis, subendothelial lucency in the glomeruli, fibrosis and small round cell infiltration in the interstitium, and hyaline droplets in the intimal spaces of arterioles and small arteries. These histological findings were consistent with late onset BMT nephropathy. This nephropathy may represent a more serious problem in the near future in Japan, since the number of BMT performed has been increasing with the establishment of a bone marrow bank.

引用

页码：489 / 493

页数：5

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